PDB: 1712 件ウェブページステータス検索Chemie searchBIRD

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6R53	Crystal structure of PPEP-1(K101R) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pro-Pro endopeptidase, ZINC ION 著者 Pichlo, C, Baumann, U. 登録日 2019-03-24 公開日 2019-06-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1. J.Biol.Chem., 294, 2019
7MKC	N74D mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74) 分子名称: IODIDE ION, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE, capsid protein 著者 Kirby, K.A, Sarafianos, S.G. 登録日 2021-04-23 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection. Viruses, 14, 2022
7MN0	N74D mutant of the HIV-1 capsid protein 分子名称: IODIDE ION, capsid protein 著者 Gres, A.T, Kirby, K.A, Sarafianos, S.G. 登録日 2021-04-30 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection. Viruses, 14, 2022
7NDZ	ThyX reconstituted with N5-carbinolamine flavin 分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ... 著者 Bou-Nader, C, Pecqueur, L, Hamdane, D. 登録日 2021-02-02 公開日 2021-07-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An enzymatic activation of formaldehyde for nucleotide methylation. Nat Commun, 12, 2021
7NDW	ThyX-FADH2 soaked with 20 mM Formaldehyde 分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ... 著者 Bou-Nader, C, Pecqueur, L, Hamdane, D. 登録日 2021-02-02 公開日 2021-07-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An enzymatic activation of formaldehyde for nucleotide methylation. Nat Commun, 12, 2021
7LI3	Structure of the LRRK2 G2019S mutant 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 著者 Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. 登録日 2021-01-26 公開日 2021-06-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural analysis of the full-length human LRRK2. Cell, 184, 2021
7LI4	Structure of LRRK2 after symmetry expansion 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 著者 Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. 登録日 2021-01-26 公開日 2021-06-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural analysis of the full-length human LRRK2. Cell, 184, 2021
7LHT	Structure of the LRRK2 dimer 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 著者 Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. 登録日 2021-01-26 公開日 2021-06-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural analysis of the full-length human LRRK2. Cell, 184, 2021
7LHW	Structure of the LRRK2 monomer 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 著者 Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. 登録日 2021-01-26 公開日 2021-06-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural analysis of the full-length human LRRK2. Cell, 184, 2021
5XPT	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Taharazako, S, Hashimoto, H. 登録日 2017-06-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
6UCL	Transcription factor deltaFosB bZIP domain self-assembly, type-I crystal 分子名称: CHLORIDE ION, Protein fosB 著者 Yin, Z, Machius, M, Rudenko, G. 登録日 2019-09-16 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.207 Å) 主引用文献 Self-assembly of the bZIP transcription factor Delta FosB. Curr Res Struct Biol, 2, 2020
5XPU	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Taharazako, S, Hashimoto, H. 登録日 2017-06-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
6V0M	Sterile alpha-motif from apoptosis signal-regulating kinase 3 分子名称: Mitogen-activated protein kinase kinase kinase 15 著者 Trevelyan, S.J, Mace, P.D. 登録日 2019-11-18 公開日 2020-04-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases. Sci.Signal., 13, 2020
6VE5	X-ray structure of human REV7 in complex with Shieldin3 (residues 41-74) 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, SULFATE ION, Shieldin complex subunit 3 著者 Cui, G, Botuyan, M.V, Mer, G. 登録日 2019-12-28 公開日 2021-01-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta. J.Biol.Chem., 297, 2021
5Y8U	Crystal structure of the C276S mutant of MAP2K7 分子名称: Dual specificity mitogen-activated protein kinase kinase 7 著者 Kinoshita, T. 登録日 2017-08-21 公開日 2017-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 High-resolution structure discloses the potential for allosteric regulation of mitogen-activated protein kinase kinase 7 Biochem. Biophys. Res. Commun., 493, 2017
5Y90	MAP2K7 mutant -C218S 分子名称: Dual specificity mitogen-activated protein kinase kinase 7, GLYCEROL 著者 Kinoshita, T, Hashimoto, T, Sogabe, Y, Matsumoto, T, Sawa, M, Fukada, H. 登録日 2017-08-22 公開日 2017-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High-resolution structure discloses the potential for allosteric regulation of mitogen-activated protein kinase kinase 7 Biochem. Biophys. Res. Commun., 493, 2017
2C1N	Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE 著者 Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. 登録日 2005-09-16 公開日 2005-11-02 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3. Mol.Cell, 20, 2005
2C1J	Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE 著者 Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. 登録日 2005-09-15 公開日 2005-11-02 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3. Mol.Cell, 20, 2005
2EJQ	Conserved hypothetical protein (TTHA0227) from Thermo thermophilus HB8 分子名称: Hypothetical protein TTHA0227, MAGNESIUM ION 著者 Rehse, P.H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-20 公開日 2007-09-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Conserved hypothetical protein (TTHA0227) from Thermo thermophilus HB8 To be Published
6WM1	Crystal structure of the Grb2 SH2 domain in complex with a tripeptide: Ac-pY-Ac6c-N-phenylpropyl 分子名称: ACE-PTR-02K-ASN-PRA, CALCIUM ION, CHLORIDE ION, ... 著者 Martin, S.F, Clements, J.H. 登録日 2020-04-20 公開日 2020-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Some thermodynamic effects of varying nonpolar surfaces in protein-ligand interactions. Eur.J.Med.Chem., 208, 2020
6W3F	Rd1NTF2_05_I64F_A80G_T94P_D101K_L106W 分子名称: Rd1NTF2_05_I64F_A80G_T94P_D101K_L106W 著者 Bick, M.J, Basanta, B, Sankaran, B, Baker, D. 登録日 2020-03-09 公開日 2020-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 An enumerative algorithm for de novo design of proteins with diverse pocket structures. Proc.Natl.Acad.Sci.USA, 117, 2020
2DYL	Crystal structure of human mitogen-activated protein kinase kinase 7 activated mutant (S287D, T291D) 分子名称: Dual specificity mitogen-activated protein kinase kinase 7 著者 Kukimoto-Niino, M, Takagi, T, Kaminishi, T, Uchikubo-Kamo, T, Terada, T, Matsuzaki, O, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-09-15 公開日 2007-08-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of human mitogen-activated protein kinase kinase 7 activated mutant (S287D, T291D) To be Published
6WS5	Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT 分子名称: 3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ... 著者 McPherson, K.S, Korzhnev, D.M. 登録日 2020-04-30 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.472 Å) 主引用文献 Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis. Chemmedchem, 16, 2021
6W3D	Rd1NTF2_05 with long sheet 分子名称: Rd1NTF2_05 著者 Bick, M.J, Basanta, B, Sankaran, B, Baker, D. 登録日 2020-03-09 公開日 2020-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 An enumerative algorithm for de novo design of proteins with diverse pocket structures. Proc.Natl.Acad.Sci.USA, 117, 2020
6W3G	Rd1NTF2_04 with long sheet 分子名称: Rd1NTF2_04 著者 Bick, M.J, Basanta, B, Sankaran, B, Baker, D. 登録日 2020-03-09 公開日 2020-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 An enumerative algorithm for de novo design of proteins with diverse pocket structures. Proc.Natl.Acad.Sci.USA, 117, 2020

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