PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4IBG	Ebola virus VP35 bound to small molecule 分子名称: GLYCEROL, PHOSPHATE ION, Polymerase cofactor VP35, ... 著者 Brown, C.S, Leung, D.W, Xu, W, Borek, D.M, Otwinowski, Z, Ramanan, P, Stubbs, A.J, Peterson, D.S, Binning, J.M, Amarasinghe, G.K. 登録日 2012-12-08 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.413 Å) 主引用文献 In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity. J.Mol.Biol., 426, 2014
4IBZ	Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation T284R 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... 著者 Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IEJ	Crystal structure of a DNA methyltransferase 1 associated protein 1 (DMAP1) from Homo sapiens at 1.45 A resolution 分子名称: CALCIUM ION, DNA methyltransferase 1-associated protein 1 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2012-12-13 公開日 2013-01-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of a DNA methyltransferase 1 associated protein 1 (DMAP1) from Homo sapiens at 1.45 A resolution To be published
4IF6	Structure of NAD-dependent protein deacetylase sirtuin-1 (closed state, 2.25 A) 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent protein deacetylase sirtuin-1, ZINC ION 著者 Davenport, A.M, Huber, F.M, Hoelz, A. 登録日 2012-12-14 公開日 2013-10-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of a nucleoporin complex To be Published
4IBN	Crystal structure of LC9-RNase H1, a type 1 RNase H with the type 2 active-site motif 分子名称: Ribonuclease H 著者 Nguyen, T.-N, You, D.-J, Kanaya, E, Koga, Y, Kanaya, S. 登録日 2012-12-09 公開日 2013-03-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal structure of metagenome-derived LC9-RNase H1 with atypical DEDN active site motif Febs Lett., 587, 2013
4ICC	Crystal structure of human AKR1B10 complexed with NADP+ and JF0064 分子名称: 2,2',3,3',5,5',6,6'-octafluorobiphenyl-4,4'-diol, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Porte, S, de Lera, A.R, Martin, M.J, de la Fuente, J.A, Klebe, G, Farres, J, Pares, X, Podjarny, A. 登録日 2012-12-10 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.752 Å) 主引用文献 Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design. Acta Crystallogr.,Sect.D, 70, 2014
4IBU	Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation T284R in sequence-specific complex with DNA 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... 著者 Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IE0	Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with pyridine-2,4-dicarboxylate (2,4-PDCA) 分子名称: Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, PYRIDINE-2,4-DICARBOXYLIC ACID, ... 著者 Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2012-12-13 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural basis for inhibition of the fat mass and obesity associated protein (FTO) J.Med.Chem., 56, 2013
4IE5	Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-[(3-hydroxypyridin-2-yl)carbonyl]glycine (MD6) 分子名称: Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, N-[(3-hydroxypyridin-2-yl)carbonyl]glycine, ... 著者 Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2012-12-13 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for inhibition of the fat mass and obesity associated protein (FTO) J.Med.Chem., 56, 2013
4IEM	Human apurinic/apyrimidinic endonuclease (APE1) with product DNA and Mg2+ 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*C)-3'), DNA (5'-D(P*(3DR)P*GP*AP*TP*CP*G)-3'), ... 著者 Tsutakawa, S.E, Mol, C.D, Arvai, A.S, Tainer, J.A. 登録日 2012-12-13 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3936 Å) 主引用文献 Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes. J.Biol.Chem., 288, 2013
4IGL	Structure of the RHS-repeat containing BC component of the secreted ABC toxin complex from Yersinia entomophaga 分子名称: GLYCEROL, POTASSIUM ION, YenB, ... 著者 Busby, J.N, Panjikar, S, Landsberg, M.J, Hurst, M.R.H, Lott, J.S. 登録日 2012-12-17 公開日 2013-08-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device Nature, 501, 2013
3G7N	Crystal Structure of a Triacylglycerol Lipase from Penicillium Expansum at 1.3 分子名称: DI(HYDROXYETHYL)ETHER, Lipase, PENTAETHYLENE GLYCOL, ... 著者 Bian, C.B, Yuan, C, Chen, L.Q, Edward, J.M, Lin, L, Jiang, L.G, Huang, Z.X, Huang, M.D. 登録日 2009-02-10 公開日 2010-02-23 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD Proteins, 78, 2010
4IJG	Crystal structure of monomeric bacteriophytochrome 分子名称: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome, DI(HYDROXYETHYL)ETHER, ... 著者 Auldridge, M.E. 登録日 2012-12-21 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Origins of fluorescence in evolved bacteriophytochromes. J.Biol.Chem., 289, 2014
2PYT	Crystal structure of a putative ethanolamine utilization protein q (eutq, stm2468) from salmonella typhimurium lt2 at 1.90 A resolution 分子名称: Ethanolamine utilization protein eutQ 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-05-16 公開日 2007-05-29 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Ethanolamine utilization protein eutQ (16421009) from Salmonella typhimurium LT2 at 1.90 A resolution To be published
4IBD	Ebola virus VP35 bound to small molecule 分子名称: 5-[(2R)-3-benzoyl-2-(4-bromothiophen-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-2-methylbenzoic acid, GLYCEROL, MAGNESIUM ION, ... 著者 Brown, C.S, Leung, D.W, Xu, W, Borek, D.M, Otwinowski, Z, Ramanan, P, Stubbs, A.J, Peterson, D.S, Binning, J.M, Amarasinghe, G.K. 登録日 2012-12-08 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity. J.Mol.Biol., 426, 2014
4IBW	Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R in sequence-specific complex with DNA 分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ... 著者 Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.791 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IM7	Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, D-MANNONIC ACID, Hypothetical oxidoreductase ydfI, ... 著者 Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K. 登録日 2013-01-02 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate To be Published
2Q3L	CRYSTAL STRUCTURE OF AN UNCHARACTERIZED PROTEIN FROM DUF3478 FAMILY WITH A SPOIIAA-LIKE FOLD (SHEW_3102) FROM SHEWANELLA LOIHICA PV-4 AT 2.25 A RESOLUTION 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, SODIUM ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-05-30 公開日 2007-06-12 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding. Acta Crystallogr.,Sect.F, 66, 2010
4IHY	Crystal structure of Fis bound to 27bp Inosine substituted DNA F29-dI (AAATTTGTTTGIICICTGAGCAAATTT) 分子名称: 27-bp DNA Strand A, 27-bp DNA Strand B, DNA-binding protein fis 著者 Hancock, S.P, Cascio, D, Johnson, R.C. 登録日 2012-12-19 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Control of DNA minor groove width and Fis protein binding by the purine 2-amino group. Nucleic Acids Res., 41, 2013
4IIT	The Phenylacetyl-CoA monooxygenase PaaABC subcomplex with phenylacetyl-CoA 分子名称: Phenylacetate-CoA oxygenase subunit PaaA, Phenylacetate-CoA oxygenase subunit PaaB, Phenylacetate-CoA oxygenase subunit PaaC, ... 著者 Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2012-12-20 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Family of phenylacetyl-CoA monooxygenases differs in subunit organization from other monooxygenases. J.Struct.Biol., 184, 2013
4IHW	Crystal structure of Fis bound to 27 bp Inosine substituted DNA F28-dI (AAATTTGTTTGAICITTGAGCAAATTT) 分子名称: 27-bp DNA Strand A, 27-bp DNA Strand B, DNA-binding protein fis 著者 Hancock, S.P, Cascio, D, Johnson, R.C. 登録日 2012-12-19 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Control of DNA minor groove width and Fis protein binding by the purine 2-amino group. Nucleic Acids Res., 41, 2013
2Q7S	Crystal structure of N-formylglutamate amidohydrolase (YP_297560.1) from Ralstonia eutropha JMP134 at 2.00 A resolution 分子名称: N-formylglutamate amidohydrolase, ZINC ION 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-06-07 公開日 2007-06-19 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of N-formylglutamate amidohydrolase (YP_297560.1) from Ralstonia eutropha JMP134 at 2.00 A resolution To be published
4ILY	Abundantly secreted chitosanase from Streptomyces sp. SirexAA-E 分子名称: Chitosanase 著者 Bianchetti, C.M, Takasuka, T.E, Bergeman, L.F, Fox, B.G. 登録日 2013-01-01 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.835 Å) 主引用文献
4IK0	Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli 分子名称: Diaminopimelate epimerase, IODIDE ION 著者 Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A. 登録日 2012-12-24 公開日 2013-02-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Dimerization of bacterial diaminopimelate epimerase is essential for catalysis J.Biol.Chem., 288, 2013
4INI	Human Histidine Triad Nucleotide Binding Protein 2 with Bound AMP 分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Maize, K.M, Wagner, C.R, Finzel, B.C. 登録日 2013-01-04 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily. Febs J., 280, 2013

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