3SBE
| Crystal structure of RAC1 P29S mutant | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2011-06-03 | 公開日 | 2012-07-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat.Genet., 44, 2012
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3TH5
| Crystal structure of wild-type RAC1 | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2011-08-18 | 公開日 | 2012-07-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat.Genet., 44, 2012
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4DLX
| H-Ras Set 1 CaCl2/DTE, ordered off | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.731 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLT
| H-Ras Set 2 Ca(OAc)2, on | 分子名称: | ACETATE ION, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLR
| H-Ras PEG 400/Ca(OAc)2, ordered off | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.319 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLY
| Set 1 CaCl2/DTT, ordered off | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLV
| H-Ras Set 2 CaCl2/DTT, ordered off | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.572 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLW
| H-Ras Set 2 Ca(OAc)2/DTT, on | 分子名称: | ACETATE ION, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLU
| H-Ras Set 1 Ca(OAc)2, on | 分子名称: | ACETATE ION, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLS
| H-Ras Set 1 CaCl2 'Mixed' | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.819 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4DLZ
| H-Ras Set 2 Ca(OAc)2/DTE, ordered off | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2012-02-06 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.662 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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3V4F
| H-Ras PEG 400/CaCl2, ordered off | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Mattos, C. | 登録日 | 2011-12-14 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.391 Å) | 主引用文献 | Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
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4FME
| EspG-Rab1-Arf6 complex | 分子名称: | ADP-ribosylation factor 6, ALUMINUM FLUORIDE, EspG protein, ... | 著者 | Shao, F, Zhu, Y. | 登録日 | 2012-06-16 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMD
| EspG-Rab1 complex structure at 3.05 A | 分子名称: | ALUMINUM FLUORIDE, DI(HYDROXYETHYL)ETHER, EspG protein, ... | 著者 | Shao, F, Zhu, Y. | 登録日 | 2012-06-16 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMB
| VirA-Rab1 complex structure | 分子名称: | ALUMINUM FLUORIDE, Cysteine protease-like virA, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Shao, F, Zhu, Y. | 登録日 | 2012-06-16 | 公開日 | 2012-09-05 | 最終更新日 | 2012-10-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMC
| EspG-Rab1 complex | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Shao, F, Zhu, Y. | 登録日 | 2012-06-16 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4GPT
| Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1 | 分子名称: | 1,2-ETHANEDIOL, 2-(2-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}ethyl)-1,3,4-oxadiazole, CHLORIDE ION, ... | 著者 | Sun, Q, Chook, Y.M. | 登録日 | 2012-08-21 | 公開日 | 2012-09-05 | 最終更新日 | 2013-01-23 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells. Leukemia, 27, 2013
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3TSO
| Structure of the cancer associated Rab25 protein in complex with FIP2 | 分子名称: | GLYCEROL, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Oda, S, Lall, P.Y, McCaffrey, M.W, Khan, A.R. | 登録日 | 2011-09-13 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of the cancer associated Rab25 protein in complex with FIP2 TO BE PUBLISHED
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3TVD
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4DKX
| Crystal Structure of the Rab 6A'(Q72L) | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-6A | 著者 | Park, H.H, Shin, Y.-C. | 登録日 | 2012-02-04 | 公開日 | 2012-10-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of Rab6A'(Q72L) mutant reveals unexpected GDP/Mg2+ binding with opened GTP-binding domain Biochem.Biophys.Res.Commun., 424, 2012
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4GMX
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4DVG
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4GZM
| Crystal structure of RAC1 F28L mutant | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2012-09-06 | 公開日 | 2012-12-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc.Natl.Acad.Sci.USA, 110, 2013
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4GZL
| Crystal structure of RAC1 Q61L mutant | 分子名称: | ISOPROPYL ALCOHOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2012-09-06 | 公開日 | 2012-12-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HAW
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