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3TH5
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BU of 3th5 by Molmil
Crystal structure of wild-type RAC1
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1
著者Ha, B.H, Boggon, T.J.
登録日2011-08-18
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
3SBE
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BU of 3sbe by Molmil
Crystal structure of RAC1 P29S mutant
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1
著者Ha, B.H, Boggon, T.J.
登録日2011-06-03
公開日2012-07-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
4DLU
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BU of 4dlu by Molmil
H-Ras Set 1 Ca(OAc)2, on
分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLW
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BU of 4dlw by Molmil
H-Ras Set 2 Ca(OAc)2/DTT, on
分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLR
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BU of 4dlr by Molmil
H-Ras PEG 400/Ca(OAc)2, ordered off
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.319 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLY
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BU of 4dly by Molmil
Set 1 CaCl2/DTT, ordered off
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLV
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BU of 4dlv by Molmil
H-Ras Set 2 CaCl2/DTT, ordered off
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.572 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLS
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BU of 4dls by Molmil
H-Ras Set 1 CaCl2 'Mixed'
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.819 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLZ
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BU of 4dlz by Molmil
H-Ras Set 2 Ca(OAc)2/DTE, ordered off
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.662 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
3V4F
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BU of 3v4f by Molmil
H-Ras PEG 400/CaCl2, ordered off
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2011-12-14
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLX
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BU of 4dlx by Molmil
H-Ras Set 1 CaCl2/DTE, ordered off
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.731 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLT
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BU of 4dlt by Molmil
H-Ras Set 2 Ca(OAc)2, on
分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4FMB
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BU of 4fmb by Molmil
VirA-Rab1 complex structure
分子名称: ALUMINUM FLUORIDE, Cysteine protease-like virA, GUANOSINE-5'-DIPHOSPHATE, ...
著者Shao, F, Zhu, Y.
登録日2012-06-16
公開日2012-09-05
最終更新日2012-10-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
4FME
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BU of 4fme by Molmil
EspG-Rab1-Arf6 complex
分子名称: ADP-ribosylation factor 6, ALUMINUM FLUORIDE, EspG protein, ...
著者Shao, F, Zhu, Y.
登録日2012-06-16
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
4FMD
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BU of 4fmd by Molmil
EspG-Rab1 complex structure at 3.05 A
分子名称: ALUMINUM FLUORIDE, DI(HYDROXYETHYL)ETHER, EspG protein, ...
著者Shao, F, Zhu, Y.
登録日2012-06-16
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
4FMC
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BU of 4fmc by Molmil
EspG-Rab1 complex
分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Shao, F, Zhu, Y.
登録日2012-06-16
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
4GPT
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BU of 4gpt by Molmil
Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1
分子名称: 1,2-ETHANEDIOL, 2-(2-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}ethyl)-1,3,4-oxadiazole, CHLORIDE ION, ...
著者Sun, Q, Chook, Y.M.
登録日2012-08-21
公開日2012-09-05
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells.
Leukemia, 27, 2013
3TSO
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BU of 3tso by Molmil
Structure of the cancer associated Rab25 protein in complex with FIP2
分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHATE ION, ...
著者Oda, S, Lall, P.Y, McCaffrey, M.W, Khan, A.R.
登録日2011-09-13
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the cancer associated Rab25 protein in complex with FIP2
TO BE PUBLISHED
3TVD
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BU of 3tvd by Molmil
Crystal Structure of Mouse RhoA-GTP complex
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
著者Swaminathan, K, Pal, K, Jobichen, C.
登録日2011-09-20
公開日2012-10-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献Crystal structure of mouse RhoA:GTPgammaS complex in a centered lattice.
J.Struct.Funct.Genom., 13, 2012
4GMX
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BU of 4gmx by Molmil
Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
著者Sun, Q, Chook, Y.M.
登録日2012-08-16
公開日2012-10-17
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.
Blood, 120, 2012
4DKX
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BU of 4dkx by Molmil
Crystal Structure of the Rab 6A'(Q72L)
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-6A
著者Park, H.H, Shin, Y.-C.
登録日2012-02-04
公開日2012-10-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Rab6A'(Q72L) mutant reveals unexpected GDP/Mg2+ binding with opened GTP-binding domain
Biochem.Biophys.Res.Commun., 424, 2012
4DVG
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BU of 4dvg by Molmil
Crystal structure of E. histolytica Formin1 bound to EhRho1-GTPgammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Diaphanous protein, MAGNESIUM ION, ...
著者Bosch, D.E, Siderovski, D.P.
登録日2012-02-23
公開日2012-11-14
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin.
Biochemistry, 51, 2012
4GZM
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BU of 4gzm by Molmil
Crystal structure of RAC1 F28L mutant
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1
著者Ha, B.H, Boggon, T.J.
登録日2012-09-06
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献RAC1P29S is a spontaneously activating cancer-associated GTPase.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GZL
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BU of 4gzl by Molmil
Crystal structure of RAC1 Q61L mutant
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Ha, B.H, Boggon, T.J.
登録日2012-09-06
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献RAC1P29S is a spontaneously activating cancer-associated GTPase.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HB4
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BU of 4hb4 by Molmil
Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
著者Sun, Q, Chook, Y.M.
登録日2012-09-27
公開日2013-01-09
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013

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