PDB: 41592 件ウェブページステータス検索Chemie searchBIRD

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7LUA	Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 SOSIP gp120, ... 著者 Manne, K, Edwards, R.J, Acharya, P. 登録日 2021-02-21 公開日 2021-03-17 最終更新日 2021-06-09 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
6K3D	Structure of multicopper oxidase mutant 分子名称: COPPER (II) ION, CU-O-CU LINKAGE, Multicopper oxidase 著者 Sakuraba, H, Ohshida, T, Satomura, T, Yoneda, K, Ohshima, T. 登録日 2019-05-17 公開日 2020-05-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.919 Å) 主引用文献 Activity enhancement of multicopper oxidase from a hyperthermophile via directed evolution, and its application as the element of a high performance biocathode. J.Biotechnol., 325, 2021
7LU9	Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Manne, K, Edwards, R.J, Acharya, P. 登録日 2021-02-21 公開日 2021-03-24 最終更新日 2021-06-09 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
5CR5	X-RAY CRYSTAL STRUCTURE AT 1.61A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A BIPHENYL PYRROLIDINE ETHER COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR. 分子名称: 1,2-ETHANEDIOL, 3-({(3R)-1-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}oxy)-N-methyl-2'-[(methylsulfonyl)amino]biphenyl-4-carboxamide, Branched-chain-amino-acid aminotransferase, ... 著者 Somers, D.O. 登録日 2015-07-22 公開日 2015-08-12 最終更新日 2015-09-02 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library. Acs Med.Chem.Lett., 6, 2015
6KLW	Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem 分子名称: CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib 著者 Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. 登録日 2019-07-30 公開日 2020-01-15 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
6KLX	Pore structure of Iota toxin binding component (Ib) 分子名称: CALCIUM ION, Iota toxin component Ib 著者 Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. 登録日 2019-07-30 公開日 2020-01-15 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
5UDK	IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. 登録日 2016-12-27 公開日 2017-03-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6KSD	Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, SULFATE ION 著者 Ramachandran, R, Shukla, A, Afsar, M. 登録日 2019-08-23 公開日 2020-08-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
7LMX	A HIGHLY SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 WITH A DISULFIDE 分子名称: Integrin inhibitor 著者 Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. 登録日 2021-02-06 公開日 2022-08-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
2G1A	Crystal structure of the complex between Apha class B acid phosphatase/phosphotransferase 分子名称: Class B acid phosphatase, MAGNESIUM ION, {[2-(6-AMINO-9H-PURIN-9-YL)ETHOXY]METHYL}PHOSPHONIC ACID 著者 Leone, R, Calderone, V, Cappelletti, E, Benvenuti, M, Mangani, S. 登録日 2006-02-14 公開日 2007-04-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the complex between Apha class B acid phosphatase/phosphotransferase To be published
7LMV	SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 分子名称: Integrin inhibitor 著者 Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. 登録日 2021-02-05 公開日 2022-08-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
6KRH	Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis 分子名称: ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... 著者 Ramachandran, R, Shukla, A, Afsar, M. 登録日 2019-08-21 公開日 2020-08-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
6KSC	Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis 分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase A, SULFATE ION 著者 Ramachandran, R, Shukla, A, Afsar, M. 登録日 2019-08-23 公開日 2020-08-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
7MEP	BG505 SOSIP.v5.2(7S) in complex with the monoclonal antibodies Rh.33172 mAb.1 and RM19R 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2(7S) - gp120, ... 著者 Antanasijevic, A, Ward, A.B. 登録日 2021-04-07 公開日 2022-01-26 最終更新日 2022-08-10 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7MDU	BG505 SOSIP MD39 in complex with the monoclonal antibodies Rh.33104 mAb.1 and RM20A3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RM20A3 mAb Heavy Chain, ... 著者 Antanasijevic, A, Ward, A.B. 登録日 2021-04-06 公開日 2022-01-26 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
5DXN	Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2 分子名称: MAGNESIUM ION, trehalose-6-phosphate phosphatase 著者 Miao, Y, Brennan, R.G. 登録日 2015-09-23 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
7MDT	BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ... 著者 Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B. 登録日 2021-04-06 公開日 2022-01-26 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
5VD6	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 6 分子名称: (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name), SULFATE ION, acetyltransferase PA4794 著者 Majorek, K.A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2017-04-01 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases. FEBS Lett., 591, 2017
5DXF	Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain 分子名称: trehalose-6-phosphate phosphatase 著者 Miao, Y, Brennan, R.G. 登録日 2015-09-23 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.563 Å) 主引用文献 Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
5DXI	Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain 分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ... 著者 Miao, Y, Brennan, R.G. 登録日 2015-09-23 公開日 2016-06-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
5DXL	Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 1 分子名称: trehalose-6-phosphate phosphatase 著者 Miao, Y, Brennan, R.G. 登録日 2015-09-23 公開日 2016-06-15 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.573 Å) 主引用文献 Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
7NBX	Lateral-open conformation of the lid-locked BAM complex (BamA E435C S665C, BamBDCE) by cryoEM 分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... 著者 Haysom, S.F. 登録日 2021-01-28 公開日 2021-06-02 最終更新日 2021-07-21 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nat Commun, 12, 2021
7ND0	lateral-open conformation of the wild-type BAM complex (BamABCDE) bound to a bactericidal Fab fragment 分子名称: Fab1 heavy chain, Fab1 light chain, Outer membrane protein assembly factor BamA, ... 著者 Iadanza, M.G, Haysom, S.H. 登録日 2021-01-29 公開日 2021-06-02 最終更新日 2021-07-21 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nat Commun, 12, 2021
8S9T	CRISPR-Cas type III-D effector complex 分子名称: CRISPR RNA, Cas10, Cas7-2x, ... 著者 Schwartz, E.A, Taylor, D.W. 登録日 2023-03-30 公開日 2024-04-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nat Commun, 15, 2024
7NCS	Lateral-open conformation of the lid-locked BAM complex (BamA E435C S665C, BamBDCE) bound by a bactericidal Fab fragment 分子名称: Fab1 heavy chain, Fab1 light chain, Outer membrane protein assembly factor BamA, ... 著者 Haysom, S.F, Machin, J.M. 登録日 2021-01-29 公開日 2021-06-02 最終更新日 2021-07-21 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nat Commun, 12, 2021

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