PDB: 4050 件ウェブページステータス検索Chemie searchBIRD

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1J14	BENZAMIDINE IN COMPLEX WITH RAT TRYPSIN MUTANT X99RT 分子名称: BENZAMIDINE, CALCIUM ION, SULFATE ION, ... 著者 Stubbs, M.T. 登録日 2002-11-30 公開日 2002-12-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Reconstructing the Binding Site of Factor Xa in Trypsin Reveals Ligand-induced Structural Plasticity J.MOL.BIOL., 325, 2003
1J17	FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99/175/190RT 分子名称: CALCIUM ION, SULFATE ION, Trypsin II, ... 著者 Stubbs, M.T. 登録日 2002-11-30 公開日 2002-12-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Reconstructing the Binding Site of Factor Xa in Trypsin Reveals Ligand-induced Structural Plasticity J.MOL.BIOL., 325, 2003
1QCP	CRYSTAL STRUCTURE OF THE RWJ-51084 BOVINE PANCREATIC BETA-TRYPSIN AT 1.8 A 分子名称: CALCIUM ION, CYCLOPENTANECARBOXYLIC ACID [1-(BENZOTHIAZOLE-2-CARBONYL)-4-GUANIDINO-BUTYL]-AMIDE, PROTEIN (BETA-TRYPSIN PROTEIN) 著者 Recacha, R, Carson, M, Costanzo, M.J, Maryanoff, B, Chattopadhyay, D. 登録日 1999-05-10 公開日 1999-05-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the RWJ-51084-bovine pancreatic beta-trypsin complex at 1.8 A. Acta Crystallogr.,Sect.D, 55, 1999
1QA0	BOVINE TRYPSIN 2-AMINOBENZIMIDAZOLE COMPLEX 分子名称: 2H-BENZOIMIDAZOL-2-YLAMINE, CALCIUM ION, TRYPSIN 著者 Whitlow, M. 登録日 1999-04-09 公開日 2000-04-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin. Acta Crystallogr.,Sect.D, 55, 1999
1K1N	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, TRYPSIN, [N-[N-(4-METHOXY-2,3,6-TRIMETHYLPHENYLSULFONYL)-L-ASPARTYL]-D-(4-AMIDINO-PHENYLALANYL)]-PIPERIDINE 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
1K1O	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, TRYPSIN, {[(1R)-2-((2S)-2-{[(3-{[AMINO(IMINO)METHYL]AMINO}PROPYL)AMINO]CARBONYL}PIPERIDINYL)-1-(CYCLOHEXYLMETHYL)-2-OXOETHYL]AMINO}ACETIC ACID 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
1K1I	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, N-ALPHA-(2-NAPHTHYLSULFONYL)-N-(3-AMIDINO-L-PHENYLALANINYL)-D-PIPECOLINIC ACID, TRYPSIN 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
1K1L	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, N-ALPHA-(2-NAPHTHYLSULFONYL)-3-AMIDINO-L-PHENYLALANINE PIPERAZIDE, SULFATE ION, ... 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
1FY8	CRYSTAL STRUCTURE OF THE DELTAILE16VAL17 RAT ANIONIC TRYPSINOGEN-BPTI COMPLEX 分子名称: CALCIUM ION, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, ... 著者 Pasternak, A, White, A, Jeffery, C.J, Ringe, D, Hedstrom, L. 登録日 2000-09-28 公開日 2000-11-08 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity. Protein Sci., 10, 2001
1K1J	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, N-ALPHA-(2-NAPHTHYLSULFONYL)-N(3-AMIDINO-L-PHENYLALANINYL)ISOPIPECOLINIC ACID METHYL ESTER, SULFATE ION, ... 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
1K1M	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, N-ALPHA-(2-NAPHTHYLSULFONYL)-N(3-AMIDINO-L-PHENYLALANINYL)-4-ACETYL-PIPERAZINE, SULFATE ION, ... 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
1K1P	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, TRYPSIN, [((1R)-2-{(2S)-2-[({4-[AMINO(IMINO)METHYL]BENZYL}AMINO)CARBONYL]AZETIDINYL}-1-CYCLOHEXYL-2-OXOETHYL)AMINO]ACETIC ACID 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
2HEX	DECAMERS OBSERVED IN THE CRYSTALS OF BOVINE PANCREATIC TRYPSIN INHIBITOR 分子名称: PROTEIN (PANCREATIC TRYPSIN INHIBITOR), SULFATE ION 著者 Lubkowski, J, Wlodawer, A. 登録日 1998-08-01 公開日 1999-08-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Decamers observed in the crystals of bovine pancreatic trypsin inhibitor. Acta Crystallogr.,Sect.D, 55, 1999
1SBW	CRYSTAL STRUCTURE OF MUNG BEAN INHIBITOR LYSINE ACTIVE FRAGMENT COMPLEX WITH BOVINE BETA-TRYPSIN AT 1.8A RESOLUTION 分子名称: CALCIUM ION, PROTEIN (BETA-TRYPSIN), PROTEIN (MUNG BEAN INHIBITOR LYSIN ACTIVE FRAGMENT), ... 著者 Huang, Q, Zhu, Y, Chi, C, Tang, Y. 登録日 1999-04-29 公開日 1999-05-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of mung bean inhibitor lysine active fragment complex with bovine beta-trypsin at 1.8A resolution. J.Biomol.Struct.Dyn., 16, 1999
1F2S	CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN BOVINE BETA-TRYPSIN AND MCTI-A, A TRYPSIN INHIBITOR OF SQUASH FAMILY AT 1.8 A RESOLUTION 分子名称: CALCIUM ION, TRYPSIN, TRYPSIN INHIBITOR A 著者 Zhu, Y, Huang, Q, Qian, M, Jia, Y, Tang, Y. 登録日 2000-05-29 公開日 2000-06-05 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal structure of the complex formed between bovine beta-trypsin and MCTI-A, a trypsin inhibitor of squash family, at 1.8-A resolution. J.Protein Chem., 18, 1999
1TRM	THE THREE-DIMENSIONAL STRUCTURE OF ASN102 MUTANT OF TRYPSIN. ROLE OF ASP102 IN SERINE PROTEASE CATALYSIS 分子名称: BENZAMIDINE, CALCIUM ION, TRYPSIN 著者 Sprang, S, Standing, T, Fletterick, R.J. 登録日 1987-10-21 公開日 1988-07-16 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis. Science, 237, 1987
1SLU	RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN 分子名称: ACETATE ION, ANIONIC TRYPSIN, CALCIUM ION, ... 著者 Brinen, L.S, Fletterick, R.J. 登録日 1996-02-07 公開日 1996-07-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray structures of a designed binding site in trypsin show metal-dependent geometry. Biochemistry, 35, 1996
1SLW	RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; NICKEL-BOUND 分子名称: ACETATE ION, ANIONIC TRYPSIN, CALCIUM ION, ... 著者 Brinen, L.S, Fletterick, R.J. 登録日 1996-02-07 公開日 1996-07-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray structures of a designed binding site in trypsin show metal-dependent geometry. Biochemistry, 35, 1996
1GBT	STRUCTURE OF AN ACYL-ENZYME INTERMEDIATE DURING CATALYSIS: (GUANIDINOBENZOYL) TRYPSIN 分子名称: 4-carbamimidamidobenzoic acid, BETA-TRYPSIN, CALCIUM ION, ... 著者 Singer, P.T, Sweet, R.M. 登録日 1991-09-17 公開日 1994-01-31 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of an acyl-enzyme intermediate during catalysis: (guanidinobenzoyl)trypsin. Biochemistry, 29, 1990
1SLV	RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; COPPER-BOUND 分子名称: ACETATE ION, ANIONIC TRYPSIN, CALCIUM ION, ... 著者 Brinen, L.S, Fletterick, R.J. 登録日 1996-02-07 公開日 1996-07-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray structures of a designed binding site in trypsin show metal-dependent geometry. Biochemistry, 35, 1996
1TIO	HIGH PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE 分子名称: BENZAMIDINE, CALCIUM ION, CYCLOHEXANE, ... 著者 Huang, Q, Zhu, G, Wang, Z, Tang, Q. 登録日 1998-09-17 公開日 1998-09-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 X-ray studies on two forms of bovine beta-trypsin crystals in neat cyclohexane. Biochim.Biophys.Acta, 1429, 1998
1SLX	RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; ZINC-BOUND 分子名称: ACETATE ION, ANIONIC TRYPSIN, CALCIUM ION, ... 著者 Brinen, L.S, Fletterick, R.J. 登録日 1996-02-07 公開日 1996-07-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray structures of a designed binding site in trypsin show metal-dependent geometry. Biochemistry, 35, 1996
1BIT	THE CRYSTAL STRUCTURE OF ANIONIC SALMON TRYPSIN IN A SECOND CRYSTAL FORM 分子名称: BENZAMIDINE, CALCIUM ION, SULFATE ION, ... 著者 Berglund, G.I. 登録日 1994-08-26 公開日 1994-11-01 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure of anionic salmon trypsin in a second crystal form. Acta Crystallogr.,Sect.D, 51, 1995
1GJ6	ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS 分子名称: 6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE, BETA-TRYPSIN, CALCIUM ION 著者 Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. 登録日 2001-04-27 公開日 2002-04-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem.Biol., 8, 2001
1EJA	STRUCTURE OF PORCINE TRYPSIN COMPLEXED WITH BDELLASTASIN, AN ANTISTASIN-TYPE INHIBITOR 分子名称: BDELLASTASIN, SODIUM ION, TRYPSIN 著者 Rester, U, Moser, M, Huber, R, Bode, W. 登録日 2000-03-02 公開日 2001-03-02 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin. Acta Crystallogr.,Sect.D, 56, 2000

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