PDB: 1372 件ウェブページステータス検索Chemie searchBIRD

---

4AII	Crystal structure of the rat REM2 GTPase - G domain bound to GDP 分子名称: GTP-BINDING PROTEIN REM 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Reymond, P, Coquard, A, Chenon, M, Zeghouf, M, El Marjou, A, Thompson, A, Menetrey, J. 登録日 2012-02-10 公開日 2012-06-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Structure of the Gdp-Bound G Domain of the Rgk Protein Rem2. Acta Crystallogr.,Sect.F, 68, 2012
8IJ9	Crystal structure of the ELKS1/Rab6B complex 分子名称: ELKS/Rab6-interacting/CAST family member 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Jin, G, Wei, Z. 登録日 2023-02-26 公開日 2023-06-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation. J.Biol.Chem., 299, 2023
1OIV	X-ray structure of the small G protein Rab11a in complex with GDP 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, RAS-RELATED PROTEIN RAB-11A, ... 著者 Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. 登録日 2003-06-26 公開日 2004-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes J.Biol.Chem., 279, 2004
1Q21	CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP 分子名称: C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Kim, S.-H. 登録日 1991-09-25 公開日 1992-07-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP. J.Mol.Biol., 217, 1991
1PLK	CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS 分子名称: C-H-RAS P21 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S. 登録日 1994-03-13 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points. Acta Crystallogr.,Sect.D, 50, 1994
1PLJ	CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS 分子名称: C-H-RAS P21 PROTEIN, GUANOSINE 5'-TRIPHOSPHATE P3-[1-(2-NITROPHENYL)ETHYL ESTER], MAGNESIUM ION 著者 Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S. 登録日 1994-03-13 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points. Acta Crystallogr.,Sect.D, 50, 1994
1PLL	CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS 分子名称: C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE 著者 Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S. 登録日 1994-03-13 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points. Acta Crystallogr.,Sect.D, 50, 1994
2W2X	Complex of Rac2 and PLCg2 spPH Domain 分子名称: 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... 著者 Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. 登録日 2008-11-04 公開日 2009-05-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2. Mol.Cell, 34, 2009
1QG2	CANINE GDP-RAN R76E MUTANT 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN) 著者 Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M. 登録日 1999-04-20 公開日 1999-06-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import. J.Mol.Biol., 289, 1999
2X1V	Crystal Structure of the activating H-Ras I163F mutant in Costello Syndrome, bound to MG-GDP 分子名称: GTPASE HRAS, GUANOSINE-5'-DIPHOSPHATE 著者 Anand, K. 登録日 2010-01-04 公開日 2010-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of the Activating H-Ras I163F Mutant in Costello Syndrome, Bound to Mg-Gdp To be Published
4DLX	H-Ras Set 1 CaCl2/DTE, ordered off 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.731 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
4DLT	H-Ras Set 2 Ca(OAc)2, on 分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
4DKX	Crystal Structure of the Rab 6A'(Q72L) 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-6A 著者 Park, H.H, Shin, Y.-C. 登録日 2012-02-04 公開日 2012-10-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Rab6A'(Q72L) mutant reveals unexpected GDP/Mg2+ binding with opened GTP-binding domain Biochem.Biophys.Res.Commun., 424, 2012
1QG4	CANINE GDP-RAN F72Y MUTANT 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN) 著者 Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M. 登録日 1999-04-20 公開日 1999-06-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import. J.Mol.Biol., 289, 1999
4DRZ	Crystal structure of human RAB14 分子名称: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-14 著者 Wang, J, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2012-02-17 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of human RAB14 to be published
4DSO	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
4DSU	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: BENZIMIDAZOLE, GTPase KRas, isoform 2B, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
4DLU	H-Ras Set 1 Ca(OAc)2, on 分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
4DST	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: 1,2-ETHANEDIOL, 2-(4,6-dichloro-2-methyl-1H-indol-3-yl)ethanamine, ACETATE ION, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
1QRA	STRUCTURE OF P21RAS IN COMPLEX WITH GTP AT 100 K 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1 著者 Scheidig, A, Burmester, C, Goody, R.S. 登録日 1999-06-12 公開日 1999-11-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins. Structure Fold.Des., 7, 1999
4DLS	H-Ras Set 1 CaCl2 'Mixed' 分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.819 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
4DSN	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: 1,2-ETHANEDIOL, GTPase KRas, isoform 2B, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
4DID	Crystal structure of Salmonella effector N-terminal domain SopB in complex with Cdc42 分子名称: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, Inositol phosphate phosphatase sopB, ... 著者 Burkinshaw, B.J, Strynadka, N.C.J. 登録日 2012-01-30 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3501 Å) 主引用文献 Structure of Salmonella Effector Protein SopB N-terminal Domain in Complex with Host Rho GTPase Cdc42. J.Biol.Chem., 287, 2012
4DLZ	H-Ras Set 2 Ca(OAc)2/DTE, ordered off 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.662 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
2G3Y	Crystal structure of the human small GTPase GEM 分子名称: GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE 著者 Ugochukwu, E, Soundararajan, M, Elkins, J, Gileadi, C, Schoch, G, Sobott, F, Fedorov, O, Bray, J, Pantic, N, Berridge, G, Burgess, N, Lee, W.H, Turnbull, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) 登録日 2006-02-21 公開日 2006-04-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the human small GTPase GEM To be Published

<9101112131415161718192021222324>