Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5QID
DownloadVisualize
BU of 5qid by Molmil
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z1787627869
分子名称: 5-chloranyl-~{N}-methyl-~{N}-[[(3~{S})-oxolan-3-yl]methyl]pyrimidin-4-amine, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1
著者MacKinnon, S, Bezerra, G.A, Krojer, T, Bradley, A.R, Talon, R, Brandao-Neto, J, Douangamath, A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Brennan, P.E, Yue, W.W.
登録日2018-05-22
公開日2018-07-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献PanDDA analysis group deposition of models with modelled events (e.g. bound ligands)
To Be Published
5QIB
DownloadVisualize
BU of 5qib by Molmil
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with FMOPL000388a
分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 5-(cyclohexylamino)pyrimidine-2,4(1H,3H)-dione, Hydroxyacid oxidase 1
著者MacKinnon, S, Bezerra, G.A, Krojer, T, Bradley, A.R, Talon, R, Brandao-Neto, J, Douangamath, A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Brennan, P.E, Yue, W.W.
登録日2018-05-22
公開日2018-07-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献PanDDA analysis group deposition of models with modelled events (e.g. bound ligands)
To Be Published
1MJY
DownloadVisualize
BU of 1mjy by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D70N
分子名称: INORGANIC PYROPHOSPHATASE
著者Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R.
登録日1997-02-08
公開日1997-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
Biochemistry Mosc., 63, 1998
3DNF
DownloadVisualize
BU of 3dnf by Molmil
Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway
分子名称: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, GLYCEROL
著者Rekittke, I.
登録日2008-07-02
公開日2008-12-30
最終更新日2020-09-09
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway.
J.Am.Chem.Soc., 2008
1LEL
DownloadVisualize
BU of 1lel by Molmil
The avidin BCAP complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin, E-AMINO BIOTINYL CAPROIC ACID
著者Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2002-04-10
公開日2002-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
J.Biol.Chem., 277, 2002
2WU5
DownloadVisualize
BU of 2wu5 by Molmil
Crystal structure of the E. coli succinate:quinone oxidoreductase (SQR) SdhD His71Met mutant
分子名称: 2-METHYL-N-PHENYL-5,6-DIHYDRO-1,4-OXATHIINE-3-CARBOXAMIDE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
著者Ruprecht, J, Yankovskaya, V, Maklashina, E, Iwata, S, Cecchini, G.
登録日2009-09-29
公開日2010-08-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Crystal Structure of the E. Coli Succinate:Quinone Oxidoreductase (Sqr) Sdhd His71met Mutant
To be Published
3JCX
DownloadVisualize
BU of 3jcx by Molmil
Canine Parvovirus complexed with Fab E
分子名称: Capsid protein 2, Fab E heavy chain, Fab E light chain
著者Organtini, L.J, Iketani, S, Huang, K, Ashley, R.E, Makhov, A.M, Conway, J.F, Parrish, C.R, Hafenstein, S.
登録日2016-03-21
公開日2016-07-20
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Near-Atomic Resolution Structure of a Highly Neutralizing Fab Bound to Canine Parvovirus.
J.Virol., 90, 2016
1MJZ
DownloadVisualize
BU of 1mjz by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D97N
分子名称: INORGANIC PYROPHOSPHATASE
著者Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R.
登録日1997-02-08
公開日1997-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
Biochemistry Mosc., 63, 1998
4KPE
DownloadVisualize
BU of 4kpe by Molmil
Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate
分子名称: (7aR,8R)-8-amino-4-cyclopropyl-12-fluoro-1-oxo-4,7,7a,8,9,10-hexahydro-1H-pyrrolo[1',2':1,7]azepino[2,3-h]quinoline-2-carboxylic acid, DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, ...
著者Laponogov, I, Pan, X.-S, Vesekov, D.A, Cirz, R.T, Wagman, A.S, Moser, H.E, Fisher, L.M, Sanderson, M.R.
登録日2013-05-13
公開日2014-11-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.43 Å)
主引用文献Exploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolones.
Open Biol, 6, 2016
4BUL
DownloadVisualize
BU of 4bul by Molmil
Novel hydroxyl tricyclics (e.g. GSK966587) as potent inhibitors of bacterial type IIA topoisomerases
分子名称: (S)-4-((4-(((2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methyl)amino)piperidin-1-yl)methyl)-3-fluoro-4-hydroxy-4H-pyrrolo[3,2,1-de][1,5]naphthyridin-7(5H)-one, 5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*AP*CP *CP*GP*CP*AP*C)-3', 5'-D(*TP*GP*TP*GP*CP*GP*GP*TP*GP*TP*AP*CP*CP*TP *AP*CP*GP*GP*CP*T)-3', ...
著者Miles, T.J, Hennessy, A.J, Bax, B, Brooks, G, Brown, B.S, Brown, P, Cailleau, N, Chen, D, Dabbs, S, Davies, D.T, Esken, J.M, Giordano, I, Hoover, J.L, Huang, J, Jones, G.E, Sukmar, S.K.K, Spitzfaden, C, Markwell, R.E, Minthorn, E.A, Rittenhouse, S, Gwynn, M.N, Pearson, N.D.
登録日2013-06-20
公開日2013-08-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Novel Hydroxyl Tricyclics (E.G., Gsk966587) as Potent Inhibitors of Bacterial Type Iia Topoisomerases.
Bioorg.Med.Chem.Lett., 23, 2013
2WU2
DownloadVisualize
BU of 2wu2 by Molmil
Crystal structure of the E. coli succinate:quinone oxidoreductase (SQR) SdhC His84Met mutant
分子名称: 2-METHYL-N-PHENYL-5,6-DIHYDRO-1,4-OXATHIINE-3-CARBOXAMIDE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
著者Ruprecht, J, Yankovskaya, V, Maklashina, E, Iwata, S, Cecchini, G.
登録日2009-09-28
公開日2010-08-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the E. Coli Succinate:Quinone Oxidoreductase (Sqr) Sdhc His84met Mutant
To be Published
3MJM
DownloadVisualize
BU of 3mjm by Molmil
His257Ala mutant of dihydroorotase from E. coli
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ...
著者Ernberg, K.E, Guss, J.M, Lee, M, Maher, M.J.
登録日2010-04-13
公開日2011-03-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献His257Ala mutant of dihydroorotase from E. coli
To be Published
1BP8
DownloadVisualize
BU of 1bp8 by Molmil
4:2:1 mithramycin:Mg++:d(ACCCGGGT)2 complex
分子名称: 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-METHYL-ANTHRACENE, 2,6-dideoxy-3-C-methyl-beta-D-ribo-hexopyranose-(1-3)-2,6-dideoxy-beta-D-galactopyranose-(1-3)-beta-D-Olivopyranose, 5'-D(*AP*CP*CP*CP*GP*GP*GP*T)-3', ...
著者Keniry, M.A, Owen, E.A, Shafer, R.H.
登録日1998-08-13
公開日1999-08-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of the 4:1 mithramycin:d(ACCCGGGT)2 complex: evidence for an interaction between the E saccharides
Biopolymers, 54, 2000
4KPF
DownloadVisualize
BU of 4kpf by Molmil
Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate
分子名称: (3aS,4R)-4-amino-13-cyclopropyl-8-fluoro-10-oxo-3a,4,5,6,10,13-hexahydro-1H,3H-pyrrolo[2',1':3,4][1,4]oxazepino[5,6-h]quinoline-11-carboxylic acid, E-site1, E-site2, ...
著者Laponogov, I, Pan, X.-S, Vesekov, D.A, Cirz, R.T, Wagman, A.S, Moser, H.E, Fisher, L.M, Sanderson, M.R.
登録日2013-05-13
公開日2014-11-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Exploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolones.
Open Biol, 6, 2016
1JQY
DownloadVisualize
BU of 1jqy by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER WITH LIGAND BMSC-0010
分子名称: (3-NITRO-5-(3-MORPHOLIN-4-YL-PROPYLAMINOCARBONYL)PHENYL)-GALACTOPYRANOSIDE, HEAT-LABILE ENTEROTOXIN B CHAIN
著者Merritt, E.A, Hol, W.G.J.
登録日2001-08-09
公開日2002-05-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Anchor-based design of improved cholera toxin and E. coli heat-labile enterotoxin receptor binding antagonists that display multiple binding modes.
Chem.Biol., 9, 2002
1JWE
DownloadVisualize
BU of 1jwe by Molmil
NMR Structure of the N-Terminal Domain of E. Coli Dnab Helicase
分子名称: PROTEIN (DNAB HELICASE)
著者Weigelt, J, Brown, S.E, Miles, C.S, Dixon, N.E, Otting, G.
登録日1999-01-22
公開日1999-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer.
Structure Fold.Des., 7, 1999
1JR0
DownloadVisualize
BU of 1jr0 by Molmil
CHOLERA TOXIN B-PENTAMER WITH LIGAND BMSC-0011
分子名称: (3-NITRO-5-(2-MORPHOLIN-4-YL-ETHYLAMINOCARBONYL)PHENYL)-GALACTOPYRANOSIDE, cholera toxin B subunit
著者Merritt, E.A, Hol, W.G.J.
登録日2001-08-09
公開日2002-05-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Anchor-based design of improved cholera toxin and E. coli heat-labile enterotoxin receptor binding antagonists that display multiple binding modes.
Chem.Biol., 9, 2002
1JYS
DownloadVisualize
BU of 1jys by Molmil
Crystal Structure of E. coli MTA/AdoHcy Nucleosidase
分子名称: ADENINE, MTA/SAH nucleosidase
著者Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L.
登録日2001-09-13
公開日2002-10-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases.
Structure, 9, 2001
4HJT
DownloadVisualize
BU of 4hjt by Molmil
Kinetic stabilization of transthyretin through covalent modification of K15 by (E)-N-(4-(4-hydroxy-3,5-dimethylstyryl)phenyl)propionamide
分子名称: N-{4-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]phenyl}propanamide, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2012-10-14
公開日2013-12-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis.
J.Am.Chem.Soc., 135, 2013
4HKH
DownloadVisualize
BU of 4hkh by Molmil
Structure of the Hcp1 protein from E. coli EAEC 042 pathovar, mutants N93W-S158W
分子名称: Putative type VI secretion protein, SULFATE ION
著者Douzi, B, Spinelli, S, Derrez, E, Blangy, S, Brunet, Y.R, Cascales, E, Cambillau, C.
登録日2012-10-15
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structure of the Hcp1 protein from E. coli EAEC 042 pathovar, mutants N93W-S158W
To be Published
2WGQ
DownloadVisualize
BU of 2wgq by Molmil
Zinc substituted E Coli Copper Amine Oxidase, a model for the precursor for 2,4,5-trihydroxyphenylalaninequinone formation
分子名称: AMINE OXIDASE, CALCIUM ION, ZINC ION
著者Moody, P.C.E, Cooper, R.A.
登録日2009-04-23
公開日2009-06-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Structure of E Coli Amine Oxidase with the Cataltyic Copper Subsituted for Zinc - a Model Precursor.
To be Published
4HPX
DownloadVisualize
BU of 4hpx by Molmil
Crystal structure of Tryptophan Synthase at 1.65 A resolution in complex with alpha aminoacrylate E(A-A) and benzimidazole in the beta site and the F9 inhibitor in the alpha site
分子名称: 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, BENZIMIDAZOLE, ...
著者Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L.
登録日2012-10-24
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.
Biochemistry, 52, 2013
3C0U
DownloadVisualize
BU of 3c0u by Molmil
Crystal structure of E.coli yaeQ protein
分子名称: CHLORIDE ION, SULFATE ION, Uncharacterized protein yaeQ
著者Chang, C, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-01-21
公開日2008-01-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of E.coli yaeQ protein.
To be Published
3ZDB
DownloadVisualize
BU of 3zdb by Molmil
Structure of E. coli ExoIX in complex with the palindromic 5ov4 DNA oligonucleotide, di-magnesium and potassium
分子名称: 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ACETATE ION, ...
著者Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J.
登録日2012-11-26
公開日2013-07-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
3ZDC
DownloadVisualize
BU of 3zdc by Molmil
Structure of E. coli ExoIX in complex with the palindromic 5ov4 DNA oligonucleotide, potassium and calcium
分子名称: 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ACETATE ION, ...
著者Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J.
登録日2012-11-26
公開日2013-07-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013

227111

件を2024-11-06に公開中

PDB statisticsPDBj update infoContact PDBjnumon