PDB: 37932 件ウェブページステータス検索Chemie searchBIRD

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8FXQ	The Crystal Sturucture of Rhizopuspepsin with a bound modified peptide inhibitor generated by de novo drug design. 分子名称: ALA-CYS-VAL-LYS, CYCLOHEXANE, Rhizopuspepsin, ... 著者 Satyshur, K.A, Rich, D.H, Ripka, A.S. 登録日 2023-01-25 公開日 2023-02-08 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Aspartic protease inhibitors designed from computer-generated templates bind as predicted. Org Lett, 3, 2001
8HS8	a bacteria protein complex 分子名称: CRISPR-associated endonuclease Cas9, a protein 著者 Zhang, H, Li, X.Z, Song, G.Y. 登録日 2022-12-17 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 a bacteria protein To Be Published
7BB8	Crystal structure of Lugdulysin, a Staphylococcus lugdunensis M30 zinc metallopeptidase 分子名称: ACETATE ION, CACODYLATE ION, CALCIUM ION, ... 著者 Ruff, M, Prevost, G, Prola, K, Levy, N. 登録日 2020-12-17 公開日 2022-07-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.506 Å) 主引用文献 Crystal structure of Staphylococcus lugdunensis protease, Lugdulysin To Be Published
7BLF	Crystal structure of ene-reductase OYE4 from Botryotinia fuckeliana (BfOYE4) 分子名称: FLAVIN MONONUCLEOTIDE, FORMIC ACID, Oxidored_FMN domain-containing protein 著者 Robescu, M.S, Bergantino, E, Hall, M, Cendron, L. 登録日 2021-01-18 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Asymmetric Proton Transfer Catalysis by Stereocomplementary Old Yellow Enzymes for C=C Bond Isomerization Reaction Acs Catalysis, 12, 2022
7BN6	Crystal structure of G. sulphuraria ene-reductase GsOYE in complex with b-angelica lactone 分子名称: (2~{R})-2-methyl-2~{H}-furan-5-one, FLAVIN MONONUCLEOTIDE, NADPH2 dehydrogenase-like protein 著者 Robescu, M.S, Bergantino, E, Hall, M, Cendron, L. 登録日 2021-01-21 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Asymmetric Proton Transfer Catalysis by Stereocomplementary Old Yellow Enzymes for C=C Bond Isomerization Reaction Acs Catalysis, 12, 2022
7BHD	FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group 分子名称: NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ... 著者 Bridot, C, Bouckaert, J, Krammer, E.-M. 登録日 2021-01-11 公開日 2022-07-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors. J.Biol.Chem., 299, 2023
8FV1	SpeG spermidine N-acetyltransferase from Staphylococcus aureus in complex with spermine 分子名称: Diamine N-acetyltransferase, SPERMINE 著者 Tsimbalyuk, S, Forwood, J.K. 登録日 2023-01-18 公開日 2023-02-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 SpeG spermidine N-acetyltransferase from Staphylococcus aureus in complex with spermine, crystal form II To Be Published
8I3E	Crystal structure of ELKS1 in complex with Piccolo 分子名称: ELKS/Rab6-interacting/CAST family member 1, MKIAA0559 protein 著者 Cai, Q, Zhang, M. 登録日 2023-01-17 公開日 2024-01-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Short-distance vesicle transport via phase separation. Cell, 187, 2024
8FJD	Structure of chlorophyllase from Triticum aestivum 分子名称: CALCIUM ION, Chlorophyllase 著者 Boggs, D, Jo, M, Bridwell-Rabb, J. 登録日 2022-12-19 公開日 2023-02-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.46 Å) 主引用文献 A structure-function analysis of chlorophyllase reveals a mechanism for activity regulation dependent on disulfide bonds. J.Biol.Chem., 299, 2023
8FZK	Dimeric human importin alpha subunit 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Importin subunit alpha-1, MAGNESIUM ION 著者 Donnelly, C.M, Stewart, M, Forwood, J.K. 登録日 2023-01-29 公開日 2023-02-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dimeric human importin alpha subunit To Be Published
8FNU	Structure of RdrA from Streptococcus suis RADAR defense system 分子名称: KAP NTPase domain-containing protein 著者 Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. 登録日 2022-12-28 公開日 2023-02-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
8HVU	Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with PF07304814 分子名称: 3C-like proteinase nsp5, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate 著者 Zeng, P, Zhang, J, Li, J. 登録日 2022-12-28 公開日 2024-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystal structures of main protease (M pro ) mutants of SARS-CoV-2 variants bound to PF-07304814. Mol Biomed, 4, 2023
8FDP	The native structure of a dodecamer: 5'-CGCAAATTTGCG-3 分子名称: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3') 著者 Ogbonna, E, Wilson, W.D. 登録日 2022-12-04 公開日 2023-02-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences. Acs Bio Med Chem Au, 3, 2023
8HZR	Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07321332 分子名称: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 著者 Zeng, X.Y, Zhang, J, Li, J. 登録日 2023-01-09 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07321332 To Be Published
8F94	Structure of an alternating AT 16-mer: 5'-GCTGGATATATCCAGC-3 分子名称: CALCIUM ION, DNA 16-mer 著者 Terrell, J.R, Ogbonna, E.N, Wilson, W.D. 登録日 2022-11-23 公開日 2023-02-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences. Acs Bio Med Chem Au, 3, 2023
8HVX	Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with PF07304814 分子名称: 3C-like proteinase nsp5, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate 著者 Zhou, X.L, Zhang, J, Li, J. 登録日 2022-12-28 公開日 2024-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structures of main protease (M pro ) mutants of SARS-CoV-2 variants bound to PF-07304814. Mol Biomed, 4, 2023
8FDR	Structure of a dodecamer complex: 5'-CGCGAAAAGCCG-3-DB1476 分子名称: 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*TP*TP*TP*CP*GP*CP*G)-3'), ... 著者 Ogbonna, E, Wilson, W.D. 登録日 2022-12-04 公開日 2023-02-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences. Acs Bio Med Chem Au, 3, 2023
8I2N	The RIPK1 kinase domain in complex with QY7-2B compound 分子名称: Receptor-interacting serine/threonine-protein kinase 1, ~{N}-methyl-1-[4-[[[1-methyl-5-(phenylmethyl)pyrazol-3-yl]carbonylamino]methyl]phenyl]benzimidazole-5-carboxamide 著者 Gong, X.Y, Li, Y, Meng, H.Y, Pan, L.F. 登録日 2023-01-14 公開日 2024-01-31 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1. Acta Pharm Sin B, 14, 2024
8HVV	Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07304814 分子名称: 3C-like proteinase nsp5, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate 著者 Zeng, X.Y, Zhang, J, Li, J. 登録日 2022-12-28 公開日 2024-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structures of main protease (M pro ) mutants of SARS-CoV-2 variants bound to PF-07304814. Mol Biomed, 4, 2023
8FG7	Apo mouse acidic mammalian chitinase, catalytic domain at 277 K 分子名称: Acidic mammalian chitinase, MAGNESIUM ION 著者 Diaz, R.E, Asthana, P, Fraser, J.S. 登録日 2022-12-12 公開日 2023-03-01 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase. Biorxiv, 2024
7C2Y	The crystal structure of COVID-2019 main protease in the apo state 分子名称: 3C-like proteinase 著者 Zhou, X.L, Zhong, F.L, Lin, C, Zhou, H, Hu, X.H, Wang, Q.S, Li, J, Zhang, J. 登録日 2020-05-10 公開日 2020-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 COVID-2019 main protease in the apo state To Be Published
7C3I	Structure of L-lysine oxidase D212A/D315A 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Kitagawa, M, Matsumoto, Y, Inagaki, K, Imada, K. 登録日 2020-05-12 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of strict substrate recognition of l-lysine alpha-oxidase from Trichoderma viride. Protein Sci., 29, 2020
7C51	Crystal structure of a Simpl-like protein from Campylobacter jejuni (native protein) 分子名称: SIMPL domain-containing protein 著者 Oh, H.B, Yoon, S.I. 登録日 2020-05-18 公開日 2020-08-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Structural analysis of a Simpl-like protein from Campylobacter jejuni. Biochem.Biophys.Res.Commun., 529, 2020
8HS7	Crystal structure of Vesicle-associated membrane protein-associated protein SCS2 from yeast 分子名称: Vesicle-associated membrane protein-associated protein SCS2, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID 著者 Xu, T. 登録日 2022-12-17 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the major sperm protein domain of SCS2 from saccharomyces cerevisiae To Be Published
7C6S	Crystal structure of the SARS-CoV-2 main protease complexed with Boceprevir 分子名称: 3C-like proteinase, boceprevir (bound form) 著者 Fu, L, Feng, Y. 登録日 2020-05-22 公開日 2020-09-02 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11, 2020

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