PDB: 4955 件ウェブページステータス検索Chemie searchBIRD

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4G3E	Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to a 6-alkynylindoline (cmp1) 分子名称: (2R)-4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydro-1H-indol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol, NF-kappa-beta-inducing kinase, SULFATE ION 著者 Hymowitz, S.G, de Leon-Boenig, G. 登録日 2012-07-13 公開日 2012-08-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4FT7	Crystal Structure of the CHK1 分子名称: 1-{5-bromo-2-[(3R)-3-hydroxypiperidin-1-yl]phenyl}-3-(5-cyanopyrazin-2-yl)urea, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTJ	Crystal Structure of the CHK1 分子名称: ISOPROPYL ALCOHOL, SULFATE ION, Serine/threonine-protein kinase Chk1, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FSQ	Crystal Structure of the CHK1 分子名称: 4'-(6,7-dimethoxyindeno[1,2-c]pyrazol-3-yl)biphenyl-4-ol, SULFATE ION, Serine/threonine-protein kinase Chk1 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FT0	Crystal Structure of the CHK1 分子名称: 2-methoxy-4-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-3-yl)benzoic acid, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTT	Crystal Structure of the CHK1 分子名称: ISOPROPYL ALCOHOL, SULFATE ION, Serine/threonine-protein kinase Chk1, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4G3F	Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to a 2-(aminothiazoly)phenol (cmp2) 分子名称: 3-{2-[(5-fluoro-2-hydroxyphenyl)amino]-1,3-thiazol-4-yl}benzonitrile, NF-kappa-beta-inducing kinase 著者 Hymowitz, S.G, de Leon-Boenig, G. 登録日 2012-07-13 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.642 Å) 主引用文献 The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4GH2	Crystal Structure of the CHK1 分子名称: 3-(3-methoxy-4-nitrophenyl)-6-[2-(morpholin-4-yl)ethoxy]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-08-07 公開日 2012-10-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTC	Crystal Structure of the CHK1 分子名称: 1-(5-cyanopyrazin-2-yl)-3-(5-phenyl-1H-pyrazol-3-yl)urea, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTN	Crystal Structure of the CHK1 分子名称: 4'-{6-methoxy-7-[2-(piperidin-1-yl)ethoxy]-1,2-dihydroindeno[1,2-c]pyrazol-3-yl}biphenyl-4-ol, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTQ	Crystal Structure of the CHK1 分子名称: 5-{7-ethyl-6-[(3S)-tetrahydrofuran-3-yloxy]-2,4-dihydroindeno[1,2-c]pyrazol-3-yl}pyridine-2-carbonitrile, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FV3	Crystal Structure of the ERK2 complexed with EK6 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK6 TO BE PUBLISHED
4FSW	Crystal Structure of the CHK1 分子名称: 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTL	Crystal Structure of the CHK1 分子名称: 4'-[7-(hydroxymethyl)-2,4-dihydroindeno[1,2-c]pyrazol-3-yl]biphenyl-4-ol, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTU	Crystal Structure of the CHK1 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FV6	Crystal Structure of the ERK2 complexed with E57 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-(2-{[(2S)-1-hydroxybutan-2-yl]amino}-5-methylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E57 TO BE PUBLISHED
4FTI	Crystal Structure of the CHK1 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4G3D	Crystal structure of human NF-kappaB inducing kinase (NIK) 分子名称: MAGNESIUM ION, NF-kappa-beta-inducing kinase 著者 Hymowitz, S.G, de Leon-Boenig, G. 登録日 2012-07-13 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4FTR	Crystal Structure of the CHK1 分子名称: 2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl]-N,N-dimethylacetamide, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FUX	Crystal Structure of the ERK2 complexed with E75 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E75 TO BE PUBLISHED
4G6O	Crystal Structure of the ERK2 分子名称: 1,2-ETHANEDIOL, 4-{4-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-07-19 公開日 2012-09-19 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E28 to be published
4GEO	P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A) 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Livnah, O, Tzarum, N. 登録日 2012-08-02 公開日 2013-05-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A) To be Published
4DTK	Novel and selective pan-PIM kinase inhibitor 分子名称: (5Z)-5-{2-[(3R)-3-aminopiperidin-1-yl]-3-(propan-2-yloxy)benzylidene}-1,3-thiazolidine-2,4-dione, 1,2-ETHANEDIOL, SULFATE ION, ... 著者 Ferguson, A.D. 登録日 2012-02-21 公開日 2012-07-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases. Bioorg.Med.Chem.Lett., 22, 2012
4DYM	Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135 分子名称: 1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE, Activin receptor type-1, GLYCEROL, ... 著者 Chaikuad, A, Sanvitale, C, Cooper, C, Canning, P, Mahajan, P, Daga, N, Petrie, K, Alfano, I, Gileadi, O, Fedorov, O, Krojer, T, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2012-02-29 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135 To be Published
4DGN	Crystal Structure of maize CK2 in complex with the inhibitor luteolin 分子名称: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Casein kinase II subunit alpha 著者 Lolli, G, Mazzorana, M, Battistutta, R. 登録日 2012-01-26 公開日 2012-08-01 最終更新日 2013-01-02 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight. Biochemistry, 51, 2012

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