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4GD0
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BU of 4gd0 by Molmil
tRNA-guanine transglycosylase Y106F, C158V mutant
分子名称: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION
著者Schmidt, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G.
登録日2012-07-31
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor.
Plos One, 8, 2013
1ECJ
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BU of 1ecj by Molmil
ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH 2 AMP PER TETRAMER
分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE
著者Muchmore, C.R, Krahn, J.M, Smith, J.L.
登録日1997-07-16
公開日1998-04-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli.
Protein Sci., 7, 1998
1ENO
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BU of 1eno by Molmil
BRASSICA NAPUS ENOYL ACP REDUCTASE/NAD BINARY COMPLEX AT PH 8.0 AND ROOM TEMPERATURE
分子名称: ENOYL ACYL CARRIER PROTEIN REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Rafferty, J.B, Rice, D.W.
登録日1995-10-18
公開日1996-10-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Common themes in redox chemistry emerge from the X-ray structure of oilseed rape (Brassica napus) enoyl acyl carrier protein reductase.
Structure, 3, 1995
7OCM
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BU of 7ocm by Molmil
K1K1H6, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hepatocyte growth factor alpha chain,Hepatocyte growth factor alpha chain
著者de Jonge, H, de Nola, G, Gherardi, E.
登録日2021-04-27
公開日2021-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist.
Life Sci Alliance, 5, 2022
7OCL
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BU of 7ocl by Molmil
K1K1, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic
分子名称: Hepatocyte growth factor alpha chain,Hepatocyte growth factor alpha chain
著者de Jonge, H, de Nola, G, Gherardi, E.
登録日2021-04-27
公開日2021-07-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist.
Life Sci Alliance, 5, 2022
6O3N
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BU of 6o3n by Molmil
Cross-alpha Amyloid-like Structure alphaAmA
分子名称: Cross-alpha Amyloid-like Structure alphaAmA
著者Zhang, S.-Q, Liu, L, DeGrado, W.F.
登録日2019-02-26
公開日2019-03-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Designed peptides that assemble into cross-alpha amyloid-like structures
Nat. Chem. Biol., 14, 2018
6OWD
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BU of 6owd by Molmil
Arginine Containing Reengineered Coiled-Coiled Dimer to Examine the Impact of Proximal Cation Identity on Hydrophobically-Driven Assembly
分子名称: CHLORIDE ION, R+7
著者Biok, N.A, Bingman, C.A, Gellman, S.H.
登録日2019-05-09
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core.
Biochemistry, 58, 2019
1MM3
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BU of 1mm3 by Molmil
Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF
分子名称: Mi2-beta(Chromodomain helicase-DNA-binding protein 4) and transcription factor WSTF, ZINC ION
著者Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P.
登録日2002-09-02
公開日2003-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Engineering a Protein Scaffold from a PHD Finger
structure, 11, 2003
8FEZ
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BU of 8fez by Molmil
Prefusion-stabilized SARS-CoV-2 spike protein
分子名称: Spike glycoprotein
著者Gonzalez, K.J, Mousa, J.J, Strauch, E.M.
登録日2022-12-07
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献A general computational design strategy for stabilizing viral class I fusion proteins.
Biorxiv, 2023
5X3F
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BU of 5x3f by Molmil
Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain
分子名称: Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,cAMP-dependent protein kinase catalytic subunit alpha
著者Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O.
登録日2017-02-05
公開日2017-06-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
4Q5S
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BU of 4q5s by Molmil
Thermus thermophilus RNA polymerase initially transcribing complex containing 6-mer RNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*GP*CP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3'), ...
著者Murakami, K.S.
登録日2014-04-17
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme.
J.Biol.Chem., 289, 2014
4PWW
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BU of 4pww by Molmil
Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR494.
分子名称: ACETIC ACID, OR494, PHOSPHATE ION
著者Vorobiev, S, Lin, Y.-R, Seetharaman, J, Xiao, R, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2014-03-21
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.471 Å)
主引用文献Crystal Structure of Engineered Protein OR494.
To be Published
7Q3J
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BU of 7q3j by Molmil
Computationally designed thioredoxin subjected to stability optimizing mutations.
分子名称: GLYCEROL, MM9
著者Norrild, R.K, Johansson, K.E, O'Shea, C, Lindorff-Larsen, K, Winther, J.R, Morth, J.P.
登録日2021-10-27
公開日2022-11-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Increasing protein stability by inferring substitution effects from high-throughput experiments.
Cell Rep Methods, 2, 2022
8TVI
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BU of 8tvi by Molmil
Langya Virus G glycoprotein (LayV G) with stabilizing mutations
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya virus attachment glycoprotein G, ZINC ION
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-08-18
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
7N2A
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BU of 7n2a by Molmil
human PXR LBD bound to compound 2
分子名称: 5-benzyl-2-(3-fluoro-2-hydroxyphenyl)-6-methyl-3-(2-phenylethyl)pyrimidin-4(3H)-one, Isoform 1C of Nuclear receptor subfamily 1 group I member 2
著者Williams, S.P, Wisely, G.B, Ramanjulu, J.M.
登録日2021-05-28
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.
Acs Med.Chem.Lett., 12, 2021
3KCF
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BU of 3kcf by Molmil
Crystal structure of TGFbRI complexed with a pyrazolone inhibitor
分子名称: 4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3H-pyrazol-3-one, PHOSPHATE ION, TGF-beta receptor type-1
著者Boriack-Sjodin, P.A.
登録日2009-10-21
公開日2009-12-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Pyrazolone based TGFbetaR1 kinase inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
6I6S
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BU of 6i6s by Molmil
Circular permutant of ribosomal protein S6, adding 9aa to C terminal of P68-69, L75A mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6, POTASSIUM ION, SODIUM ION
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
2G2Y
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BU of 2g2y by Molmil
Structure of E.coli FabD complexed with malonate
分子名称: MALONATE ION, Malonyl CoA-acyl carrier protein transacylase
著者Oefner, C.
登録日2006-02-17
公開日2006-05-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography.
Acta Crystallogr.,Sect.D, 62, 2006
2G1H
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BU of 2g1h by Molmil
Structure of E.coli FabD complexed with glycerol
分子名称: GLYCEROL, Malonyl CoA-acyl carrier protein transacylase
著者Oefner, C.
登録日2006-02-14
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography.
Acta Crystallogr.,Sect.D, 62, 2006
4V6I
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BU of 4v6i by Molmil
Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ...
著者Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
登録日2010-10-12
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
2G2Z
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BU of 2g2z by Molmil
Structure of E.coli FabD complexed with malonyl-CoA
分子名称: COENZYME A, MALONIC ACID, Malonyl CoA-acyl carrier protein transacylase
著者Oefner, Christian
登録日2006-02-17
公開日2006-06-27
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography.
Acta Crystallogr.,Sect.D, 62, 2006
4WAC
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BU of 4wac by Molmil
Crystal Structure of TarM
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Koc, C, Stehle, T, Xia, G, Peschel, A.
登録日2014-08-29
公開日2015-02-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid.
J.Biol.Chem., 290, 2015
6I6U
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BU of 6i6u by Molmil
Circular permutant of ribosomal protein S6, adding 9aa to N terminal of P81-82, L75A mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
5XBY
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BU of 5xby by Molmil
Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion)
分子名称: cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A
著者Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O.
登録日2017-03-21
公開日2017-07-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
8IQF
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BU of 8iqf by Molmil
Cryo-EM structure of the dimeric human CAF1-H3-H4 complex
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
著者Liu, C.P, Yu, Z.Y, Xu, R.M.
登録日2023-03-16
公開日2023-08-16
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023

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