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6BZE
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Cryo-EM structure of BCL10 CARD filament
分子名称: B-cell lymphoma/leukemia 10
著者David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H.
登録日2017-12-23
公開日2018-02-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1G4W
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BU of 1g4w by Molmil
CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP
分子名称: PROTEIN TYROSINE PHOSPHATASE SPTP
著者Stebbins, C.E, Galan, J.E.
登録日2000-10-28
公開日2001-01-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.
Mol.Cell, 6, 2000
6BZO
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Mtb RNAP Holo/RbpA/Fidaxomicin/upstream fork DNA
分子名称: DNA (26-MER), DNA (32-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2017-12-25
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
1A9Q
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE
分子名称: HYPOXANTHINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
5O0Z
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Structure of laspartomycin C in complex with geranyl-phosphate
分子名称: ACETIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Vlieg, H.C, Kleijn, L.H.J, Martin, N.I, Janssen, B.J.C.
登録日2017-05-17
公開日2017-11-15
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献A High-Resolution Crystal Structure that Reveals Molecular Details of Target Recognition by the Calcium-Dependent Lipopeptide Antibiotic Laspartomycin C.
Angew. Chem. Int. Ed. Engl., 56, 2017
1A9R
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH HYPOXANTHINE AND SULFATE
分子名称: HYPOXANTHINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1AME
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BU of 1ame by Molmil
CRYSTAL STRUCTURE OF TYPE III ANTIFREEZE PROTEIN AT 4 C
分子名称: TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12
著者Jia, Z, Leinala, E, Ye, Q.
登録日1997-06-13
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of type III antifreeze protein at 277 K.
Acta Crystallogr.,Sect.D, 54, 1998
3M2N
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BU of 3m2n by Molmil
Crystal structure of human carbonic anhydrase isozyme II with 4-{2-[N-(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide
分子名称: 4-{2-[(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ...
著者Grazulis, S, Manakova, E, Golovenko, D.
登録日2010-03-08
公開日2011-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases.
Eur.J.Med.Chem., 51, 2012
4EG8
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Trypanosoma brucei methionyl-tRNA synthetase in complex with compound Chem 89
分子名称: 2-aminoquinolin-8-ol, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4RCO
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1.9 Angstrom Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus, in Complex with Sialyl-LewisX.
分子名称: CHLORIDE ION, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, Putative uncharacterized protein
著者Minasov, G, Nocadello, S, Shuvalova, L, Filippova, E, Halavaty, A, Dubrovska, I, Flores, K, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-09-16
公開日2014-10-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献1.9 Angstrom Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus, in Complex with Sialyl-LewisX.
TO BE PUBLISHED
2JDK
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Lectin PA-IIL of P.aeruginosa complexed with disaccharide derivative
分子名称: CALCIUM ION, FUCOSE-BINDING LECTIN PA-IIL, METHYL 2H-1,2,3-TRIAZOLE-4-CARBOXYLATE, ...
著者Marotte, K, Sabin, C, Preville, C, Pymbock, M, Deguise, I, Wimmerova, M, Mitchell, E.P, Imberty, A, Roy, R.
登録日2007-01-10
公開日2007-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献X-Ray Structures and Thermodynamics of the Interaction of Pa-Iil from Pseudomonas Aeruginosa with Disaccharide Derivatives.
Chemmedchem, 2, 2007
4N5M
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BU of 4n5m by Molmil
Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha in complexed with acetoacetyl-CoA
分子名称: ACETOACETYL-COENZYME A, Acetoacetyl-CoA reductase, GLYCEROL
著者Kim, J.-E, Kim, S, Kim, K.-J.
登録日2013-10-10
公開日2013-12-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha
Biochem.Biophys.Res.Commun., 443, 2014
1TXE
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BU of 1txe by Molmil
Solution structure of the active-centre mutant Ile14Ala of the histidine-containing phosphocarrier protein (HPr) from Staphylococcus carnosus
分子名称: Phosphocarrier protein HPr
著者Moeglich, A, Koch, B, Hengstenberg, W, Brunner, E, Kalbitzer, H.R, Structural Proteomics in Europe (SPINE)
登録日2004-07-04
公開日2005-03-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the active-centre mutant I14A of the histidine-containing phosphocarrier protein from Staphylococcus carnosus
Eur.J.Biochem., 271, 2004
1K50
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BU of 1k50 by Molmil
A V49A Mutation Induces 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus
分子名称: Protein L
著者O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
登録日2001-10-09
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
6C40
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CheY41PyTyrD54K from Thermotoga maritima
分子名称: COPPER (II) ION, Chemotaxis protein CheY
著者Merz, G.E, Muok, A.R, Crane, B.R.
登録日2018-01-11
公開日2018-10-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Site-Specific Incorporation of a Cu2+Spin Label into Proteins for Measuring Distances by Pulsed Dipolar Electron Spin Resonance Spectroscopy.
J Phys Chem B, 122, 2018
5O8R
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BU of 5o8r by Molmil
The crystal structure of DfoA bound to FAD and NADP; the desferrioxamine biosynthetic pathway cadaverine monooxygenase from the fire blight disease pathogen Erwinia amylovora
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-lysine 6-monooxygenase involved in desferrioxamine biosynthesis, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S.
登録日2017-06-14
公開日2018-02-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J. Struct. Biol., 202, 2018
3STU
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BU of 3stu by Molmil
Crystal Structure of tomato Methylketone Synthase I complexed with methyl-3-hydroxydodecanoate
分子名称: DECANOIC ACID, Methylketone synthase 1, methyl (3S)-3-hydroxydodecanoate
著者Auldridge, M.E, Austin, M.B, Noel, J.P.
登録日2011-07-11
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato.
Plant Cell, 24, 2012
1AN8
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CRYSTAL STRUCTURE OF THE STREPTOCOCCAL SUPERANTIGEN SPE-C
分子名称: STREPTOCOCCAL PYROGENIC EXOTOXIN C
著者Roussel, A, Baker, E.N.
登録日1997-06-27
公開日1998-04-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules.
Nat.Struct.Biol., 4, 1997
4NB1
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BU of 4nb1 by Molmil
Crystal Structure of FosB from Staphylococcus aureus at 1.80 Angstrom Resolution with L-Cysteine-Cys9 Disulfide
分子名称: CYSTEINE, Metallothiol transferase FosB, SULFATE ION
著者Cook, P.D, Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Armstrong, R.N.
登録日2013-10-22
公開日2014-02-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus.
Biochemistry, 53, 2014
1XAI
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CRYSTAL STRUCTURE OF STAPHLYOCOCCUS AUREUS 3-DEHYDROQUINATE SYNTHASE (DHQS) IN COMPLEX WITH ZN2+, NAD+ AND CARBAPHOSPHONATE
分子名称: 3-dehydroquinate synthase, ZINC ION, [1R-(1ALPHA,3BETA,4ALPHA,5BETA)]-5-(PHOSPHONOMETHYL)-1,3,4-TRIHYDROXYCYCLOHEXANE-1-CARBOXYLIC ACID
著者Nichols, C.E, Ren, J, Leslie, K, Dhaliwal, B, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K.
登録日2004-08-25
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Comparison of ligand induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases.
J.Mol.Biol., 343, 2004
5WVX
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Crystal Structure of bifunctional Kunitz type Trypsin /amylase inhibitor (AMTIN) from the tubers of Alocasia macrorrhiza
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, CITRIC ACID, Trypsin/chymotrypsin inhibitor
著者Palayam, M, Radhakrishnan, M, Lakshminarayanan, K, Balu, K.E, Ganapathy, J, Krishnasamy, G.
登録日2016-12-29
公開日2018-06-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition.
Int. J. Biol. Macromol., 113, 2018
6BS0
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JAK2 JH2 in complex with 63552444
分子名称: 4-(5-aminopyrazin-2-yl)-1H-pyrrolo[2,3-b]pyridin-6-amine, GLYCEROL, Tyrosine-protein kinase JAK2
著者Puleo, D.E, Schlessinger, J.
登録日2017-12-01
公開日2018-08-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.541 Å)
主引用文献JAK2 JH2 Binders
To Be Published
5FFX
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S. aureus MepR G34K Mutant
分子名称: GLYCEROL, MarR family regulatory protein, SULFATE ION
著者Newman, C.E, Birukou, I, Brennan, R.G.
登録日2015-12-19
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献S. aureus MepR G34K Mutant
To Be Published
1A5T
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CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III
分子名称: DELTA PRIME, ZINC ION
著者Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J.
登録日1998-02-18
公開日1998-05-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 91, 1997
5O7O
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The crystal structure of DfoC, the desferrioxamine biosynthetic pathway acetyltransferase/Non-Ribosomal Peptide Synthetase (NRPS)-Independent Siderophore (NIS) from the fire blight disease pathogen Erwinia amylovora
分子名称: Desferrioxamine siderophore biosynthesis protein dfoC
著者Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S.
登録日2017-06-09
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J. Struct. Biol., 202, 2018

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