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2RKW
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Intermediate position of ATP on its trail to the binding pocket inside the subunit B mutant R416W of the energy converter A1Ao ATP synthase
分子名称: V-type ATP synthase beta chain
著者Kumar, A, Manimekalai, M.S.S, Balakrishna, A.M, Hunke, C, Gruber, G.
登録日2007-10-18
公開日2008-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase
Proteins, 75, 2009
5GUK
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Crystal structure of apo form of cyclolavandulyl diphosphate synthase (CLDS) from Streptomyces sp. CL190
分子名称: CHLORIDE ION, Cyclolavandulyl diphosphate synthase
著者Tomita, T, Kobayashi, M, Nishiyama, M, Kuzuyama, T.
登録日2016-08-29
公開日2017-08-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Mechanism of the Monoterpene Cyclolavandulyl Diphosphate Synthase that Catalyzes Consecutive Condensation and Cyclization.
Angew. Chem. Int. Ed. Engl., 56, 2017
7CMC
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CRYSTAL STRUCTURE OF DEOXYHYPUSINE SYNTHASE FROM PYROCOCCUS HORIKOSHII
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable deoxyhypusine synthase
著者Yu, J, Gai, Z.Q, Okada, C, Yao, M.
登録日2020-07-27
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Flexible NAD+Binding in Deoxyhypusine Synthase Reflects the Dynamic Hypusine Modification of Translation Factor IF5A.
Int J Mol Sci, 21, 2020
2JLC
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Crystal structure of E.coli MenD, 2-succinyl-5-enolpyruvyl-6-hydroxy- 3-cyclohexadiene-1-carboxylate synthase - native protein
分子名称: 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE, MANGANESE (II) ION, THIAMINE DIPHOSPHATE
著者Dawson, A, Fyfe, P.K, Hunter, W.N.
登録日2008-09-08
公開日2008-10-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Specificity and Reactivity in Menaquinone Biosynthesis: The Structure of Escherichia Coli Mend (2-Succinyl-5-Enolpyruvyl-6-Hydroxy-3-Cyclohexadiene-1-Carboxylate Synthase).
J.Mol.Biol., 384, 2008
6AXO
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F96S Epi-isozizaene synthase
分子名称: Epi-isozizaene synthase
著者Blank, P.N, Barrow, G.H, Christianson, D.W.
登録日2017-09-07
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.
Biochemistry, 56, 2017
2NSI
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HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-FREE, SEITU COMPLEX
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYLISOTHIOUREA, PROTEIN (NITRIC OXIDE SYNTHASE), ...
著者Li, H, Raman, C.S, Glaser, C.B, Blasko, E, Young, T.A, Parkinson, J.F, Whitlow, M, Poulos, T.L.
登録日1999-01-11
公開日2000-01-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase.
J.Biol.Chem., 274, 1999
3VJB
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Crystal structure of the human squalene synthase
分子名称: Squalene synthase
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3A5Q
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Benzalacetone synthase from Rheum palmatum
分子名称: Benzalacetone synthase
著者Morita, H, Kato, R, Abe, I, Sugio, S, Kohno, T.
登録日2009-08-10
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for benzalacetone synthase from Rheum palmatum
Proc.Natl.Acad.Sci.USA, 107, 2010
3A5S
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Benzalacetone synthase (I207L/L208F)
分子名称: Benzalacetone synthase
著者Morita, H, Kato, R, Abe, I, Sugio, S, Kohno, T.
登録日2009-08-10
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for benzalacetone synthase from Rheum palmatum
Proc.Natl.Acad.Sci.USA, 107, 2010
5E0K
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X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A
分子名称: PHOSPHATE ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain 1
著者Buller, A.R, Murciano-Calles, J, Arnold, F.H.
登録日2015-09-29
公開日2015-11-11
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation.
Proc.Natl.Acad.Sci.USA, 112, 2015
1DHP
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DIHYDRODIPICOLINATE SYNTHASE
分子名称: DIHYDRODIPICOLINATE SYNTHASE, POTASSIUM ION
著者Mirwaldt, C, Korndoerfer, I, Huber, R.
登録日1995-02-09
公開日1997-02-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution.
J.Mol.Biol., 246, 1995
3VTE
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Crystal structure of tetrahydrocannabinolic acid synthase from Cannabis sativa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, Tetrahydrocannabinolic acid synthase
著者Shoyama, Y, Tamada, T, Kurihara, K, Takeuchi, A, Taura, F, Arai, S, Blaber, M, Shoyama, Y, Morimoto, S, Kuroki, R.
登録日2012-05-28
公開日2012-07-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure and function of 1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa
J.Mol.Biol., 423, 2012
7E38
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Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with yatein and succinate
分子名称: (3~{R},4~{R})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one, (3~{S},4~{S})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one, Deoxypodophyllotoxin synthase, ...
著者Wu, M.-H, Chang, W.-c, Chien, T.-C, Chan, N.-L.
登録日2021-02-08
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase.
Proc.Natl.Acad.Sci.USA, 119, 2022
3B2Q
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Intermediate position of ATP on its trail to the binding pocket inside the subunit B mutant R416W of the energy converter A1Ao ATP synthase
分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, ...
著者Kumar, A, Manimekalai, M.S.S, Balakrishna, A.M, Hunke, C, Gruber, G.
登録日2007-10-19
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase
Proteins, 75, 2009
4Z11
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Latent aurone synthase (polyphenol oxidase) from natural source
分子名称: Aurone synthase, COPPER (II) ION
著者Molitor, C, Mauracher, S.G, Rompel, A.
登録日2015-03-26
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases.
Proc.Natl.Acad.Sci.USA, 113, 2016
1NSI
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HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-BOUND, L-ARG COMPLEX
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, GLYCEROL, ...
著者Li, H, Raman, C.S, Glaser, C.B, Blasko, E, Young, T.A, Parkinson, J.F, Whitlow, M, Poulos, T.L.
登録日1999-01-10
公開日2000-01-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase.
J.Biol.Chem., 274, 1999
4Z0Y
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Active aurone synthase (polyphenol oxidase), copper B : sulfohistidine ~ 1.4 : 1
分子名称: Aurone synthase, COPPER (II) ION, GLYCEROL
著者Molitor, C, Mauracher, S.G, Rompel, A.
登録日2015-03-26
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases.
Proc.Natl.Acad.Sci.USA, 113, 2016
5B1I
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Crystal structure of K42A mutant of cystathionine beta-synthase from Lactobacillus plantarum in a complex with L-methionine
分子名称: Cystathionine beta-synthase, N-[(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXYPHOSPHORANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLENE]METHIONINE, SULFATE ION
著者Matoba, Y, Sugiyama, M.
登録日2015-12-04
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystallographic and mutational analyses of cystathionine beta-synthase in the H2 S-synthetic gene cluster in Lactobacillus plantarum
Protein Sci., 26, 2017
3EIU
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A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A1Ao ATP synthase
分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ADENOSINE-5'-TRIPHOSPHATE, V-type ATP synthase beta chain
著者Manimekalai, S.M.S, Kumar, A, Balakrishna, A.M, Gruber, G.
登録日2008-09-17
公開日2009-02-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.43 Å)
主引用文献A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A(1)A(O) ATP synthase
J.Struct.Biol., 166, 2009
3VC3
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Crystal structure of beta-cyanoalanine synthase K95A mutant in soybean
分子名称: N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE, beta-cyanoalnine synthase
著者Yi, H, Jez, J.M.
登録日2012-01-03
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.766 Å)
主引用文献Structure of Soybean beta-Cyanoalanine Synthase and the Molecular Basis for Cyanide Detoxification in Plants.
Plant Cell, 24, 2012
1B02
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CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE A FROM BACILLUS SUBTILIS
分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, PROTEIN (THYMIDYLATE SYNTHASE)
著者Fox, K.M, Maley, F, Garibian, A, Changchien, L, Vanroey, P.
登録日1998-11-16
公開日1999-03-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of thymidylate synthase A from Bacillus subtilis.
Protein Sci., 8, 1999
3DSR
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ADP in transition binding site in the subunit B of the energy converter A1Ao ATP synthase
分子名称: ADENOSINE-5'-DIPHOSPHATE, V-type ATP synthase beta chain
著者Kumar, A, Manimekalai, S.M.S, Balakrishna, A.M, Gruber, G.
登録日2008-07-14
公開日2009-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the nucleotide-binding subunit B of the energy producer A1A0 ATP synthase in complex with adenosine diphosphate
Acta Crystallogr.,Sect.D, 64, 2008
1EA0
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Alpha subunit of A. brasilense glutamate synthase
分子名称: 2-OXOGLUTARIC ACID, FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, ...
著者Binda, C, Bossi, R.T, Vanoni, M.A, Mattevi, A.
登録日2000-11-02
公開日2001-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cross-Talk and Ammonia Channeling between Active Centers in the Unexpected Domain Arrangement of Glutamate Synthase
Structure, 8, 2000
2R98
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Crystal Structure of N-acetylglutamate synthase (selenoMet substituted) from Neisseria gonorrhoeae
分子名称: ACETYL COENZYME *A, Putative acetylglutamate synthase
著者Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M.
登録日2007-09-12
公開日2008-01-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
1PS1
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PENTALENENE SYNTHASE
分子名称: PENTALENENE SYNTHASE, TRIMETHYL LEAD ION
著者Lesburg, C.A, Christianson, D.W.
登録日1997-03-23
公開日1998-03-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology.
Science, 277, 1997

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