6QB5
 
 | | Crystal structure of the N-terminal region of human cohesin subunit STAG1 | | 分子名称: | Cohesin subunit SA-1, SODIUM ION | | 著者 | Newman, J.A, Katis, V.L, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2018-12-20 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.
Life Sci Alliance, 3, 2020
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6R7O
 | | Crystal structure of the central region of human cohesin subunit STAG1 | | 分子名称: | Cohesin subunit SA-1 | | 著者 | Newman, J.A, katis, V.L, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-03-29 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.
Life Sci Alliance, 3, 2020
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5QSX
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 | | 分子名称: | 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-07-16 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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6RRC
 | | Crystal structure of the N-terminal region of human cohesin subunit STAG1 in complex with RAD21 peptide | | 分子名称: | Cohesin subunit SA-1, Double-strand-break repair protein rad21 homolog, SULFATE ION | | 著者 | Newman, J.A, Katis, V.L, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-17 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.
Life Sci Alliance, 3, 2020
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5QSY
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z755044716 | | 分子名称: | Cohesin subunit SA-1, N-ethyl-1H-1,2,3-triazole-4-carboxamide | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSQ
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540 | | 分子名称: | Cohesin subunit SA-1, ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QST
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 | | 分子名称: | (3S)-N-methyl-N-phenylpyrrolidine-3-carboxamide, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSN
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1272480091 | | 分子名称: | (2R)-2-(methoxymethyl)-4-(pyridin-2-yl)morpholine, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSO
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z466628048 | | 分子名称: | Cohesin subunit SA-1, N-[(4-methyl-1,3-thiazol-2-yl)methyl]-1H-pyrazole-5-carboxamide | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSU
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 | | 分子名称: | 4-[(furan-2-yl)methyl]-1lambda~6~,4-thiazinane-1,1-dione, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSM
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z57261895 | | 分子名称: | 2-cyclohexyl-N-(4H-1,2,4-triazol-4-yl)acetamide, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSV
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 | | 分子名称: | Cohesin subunit SA-1, N-benzyl-1-(4-fluorophenyl)methanamine | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSP
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434929 | | 分子名称: | 4-[(4-methylphenyl)methyl]-1,4-thiazinane 1,1-dioxide, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSW
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 | | 分子名称: | 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSS
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z33452282 | | 分子名称: | Cohesin subunit SA-1, N-(2-hydroxy-4-methylphenyl)-2-methylbenzamide | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5QSZ
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1267773786 | | 分子名称: | Cohesin subunit SA-1, N-ethyl-6-methylpyridazin-3-amine | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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6RRK
 | | Crystal structure of the central region of human cohesin subunit STAG1 in complex with RAD21 peptide | | 分子名称: | Cohesin subunit SA-1, Double-strand-break repair protein rad21 homolog | | 著者 | Newman, J.A, katis, V.L, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-20 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.
Life Sci Alliance, 3, 2020
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5QSR
 | | PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z136583524 | | 分子名称: | 2-methyl-N-(pyridin-4-yl)furan-3-carboxamide, Cohesin subunit SA-1 | | 著者 | Newman, J.A, Katis, V.L, Gavard, A.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-05-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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6WG3
 | | Cryo-EM structure of human Cohesin-NIPBL-DNA complex | | 分子名称: | Cohesin subunit SA-1, DNA (51-MER), Double-strand-break repair protein rad21 homolog, ... | | 著者 | Shi, Z.B, Gao, H, Bai, X.C, Yu, H. | | 登録日 | 2020-04-04 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | | 主引用文献 | Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
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7W1M
 | | Cryo-EM structure of human cohesin-CTCF-DNA complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cohesin subunit SA-1, ... | | 著者 | Shi, Z.B, Bai, X.C, Yu, H. | | 登録日 | 2021-11-19 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | CTCF and R-loops are boundaries of cohesin-mediated DNA looping.
Mol.Cell, 83, 2023
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