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PDB: 40 件
6SLR
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BU of 6slr by Molmil
Structure of saposin B in complex with atovaquone
分子名称: 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, GLYCEROL, Prosaposin
著者Zubieta, C, Milliken, B, Doyle, R.
登録日2019-08-20
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structure of saposin B in complex with atovaquone
To Be Published
9AXG
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BU of 9axg by Molmil
Human saposin B in the presence of globotriaosylceramide-NBD
分子名称: MALONATE ION, Saposin-B
著者Sawyer, T.K, Garman, S.C.
登録日2024-03-06
公開日2024-03-13
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Human Saposin B Ligand Binding and Presentation to alpha-Galactosidase A.
Biorxiv, 2024
4V2O
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BU of 4v2o by Molmil
Structure of saposin B in complex with chloroquine
分子名称: N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, SAPOSIN-B
著者Zubieta, C, Lai, X, Doyle, R.P.
登録日2014-10-13
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献The Lysosomal Protein Saposin B Binds Chloroquine.
Chemmedchem, 11, 2016
2JSA
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BU of 2jsa by Molmil
Solution structure of Caenopore-5 (81 Pro Trans confomer)
分子名称: Saposin-like protein family protein 5
著者Mysliwy, J, Grotzinger, J.
登録日2007-07-02
公開日2008-10-14
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
2JS9
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BU of 2js9 by Molmil
Structure of caenopore-5 (81 Pro cis conformer)
分子名称: Saposin-like protein family protein 5
著者Mysliwy, J, Grotzinger, J.
登録日2007-07-02
公開日2008-10-14
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
6VZE
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BU of 6vze by Molmil
C-terminal domain of mouse surfactant protein B crystallized at low pH
分子名称: Pulmonary surfactant-associated protein B, SULFATE ION
著者Rapoport, T.A, Bodnar, N.O.
登録日2020-02-28
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
6VZ0
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BU of 6vz0 by Molmil
C-terminal domain of mouse surfactant protein B crystallized at high pH
分子名称: Pulmonary surfactant-associated protein B, ZINC ION
著者Rapoport, T.A, Bodnar, N.O.
登録日2020-02-27
公開日2020-11-25
最終更新日2021-01-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
1OF9
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BU of 1of9 by Molmil
Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)
分子名称: PORE-FORMING PEPTIDE AMEOBAPORE A
著者Hecht, O, Schleinkofer, K, Bruhn, H, Leippe, M, Van Nuland, N, Dingley, A.J, Grotzinger, J.
登録日2003-04-09
公開日2004-02-26
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of the Pore-Forming Protein of Entamoeba Histolytica
J.Biol.Chem., 279, 2004
1N69
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BU of 1n69 by Molmil
Crystal structure of human saposin B
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, SAPOSIN B
著者Ahn, V.E, Faull, K.F, Whitelegge, J.P, Fluharty, A.L, Prive, G.G.
登録日2002-11-08
公開日2003-01-07
最終更新日2021-06-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of saposin B reveals a dimeric shell for lipid binding
Proc.Natl.Acad.Sci.USA, 100, 2003
1L9L
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BU of 1l9l by Molmil
GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ...
著者Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D.
登録日2002-03-25
公開日2002-11-06
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (0.92 Å)
主引用文献Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
J.Mol.Biol., 325, 2002
4DDJ
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BU of 4ddj by Molmil
Crystal structure of saposin A in complex with lauryldimethylamine-N-oxide (LDAO)
分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Saposin-A
著者Popovic, K, Prive, G.G.
登録日2012-01-18
公開日2012-02-15
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of saposin A lipoprotein discs.
Proc.Natl.Acad.Sci.USA, 109, 2012
7P4T
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BU of 7p4t by Molmil
Tetrameric structure of murine SapA
分子名称: Saposin-A
著者Shamin, M, Deane, J.E.
登録日2021-07-13
公開日2022-05-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献A Tetrameric Assembly of Saposin A: Increasing Structural Diversity in Lipid Transfer Proteins.
Contact, 4, 2021
8EQU
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BU of 8equ by Molmil
Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein, Saposin A, ...
著者Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
登録日2022-10-09
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
7MBK
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BU of 7mbk by Molmil
N-terminal domain of mouse surfactant protein B, 6W mutant
分子名称: Pulmonary surfactant-associated protein B
著者Milicic, G, Rapoport, T.A.
登録日2021-03-31
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
2Z9A
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BU of 2z9a by Molmil
Crystal Structure of Human Saposin C Dimer in Open Conformation
分子名称: GLYCEROL, Proactivator polypeptide
著者Rossmann, M, Saenger, W, Maier, T.
登録日2007-09-18
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
5U85
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Murine saposin-D (SapD), open conformation
分子名称: Saposin-D
著者Gebai, A, Gorelik, A, Illes, K, Nagar, B.
登録日2016-12-13
公開日2018-06-13
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of saposin D in an open conformation.
J. Struct. Biol., 204, 2018
3RFI
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BU of 3rfi by Molmil
Crystal structure of the saposin-like domain of plant aspartic protease from Solanum tuberosum
分子名称: Asp
著者Bhaumik, P, Wlodawer, A.
登録日2011-04-06
公開日2011-06-15
最終更新日2011-08-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Mechanism of the Saposin-like Domain of a Plant Aspartic Protease.
J.Biol.Chem., 286, 2011
9AVS
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BU of 9avs by Molmil
Human alpha-galactosidase A in complex with saposin B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
著者Sawyer, T.K, Garman, S.C.
登録日2024-03-04
公開日2024-04-17
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.53 Å)
主引用文献Human Saposin B Ligand Binding and Presentation to alpha-Galactosidase A.
Biorxiv, 2024
3BQP
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BU of 3bqp by Molmil
Crystal Structure of Human Saposin D (orthorhombic)
分子名称: MAGNESIUM ION, Proactivator polypeptide
著者Prive, G.G, Popovic, K.
登録日2007-12-20
公開日2008-02-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
4UEX
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BU of 4uex by Molmil
Structure of human Saposin A at lysosomal pH
分子名称: PROSAPOSIN
著者Hill, C.H, Read, R.J, Deane, J.E.
登録日2014-12-20
公開日2015-07-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Human Saposin a at Lysosomal Ph.
Acta Crystallogr.,Sect.D, 71, 2015
3BQQ
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BU of 3bqq by Molmil
Crystal Structure of Human Saposin D (triclinic)
分子名称: PROACTIVATOR POLYPEPTIDE
著者Prive, G.G, Popovic, K.
登録日2007-12-20
公開日2008-02-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
6VZD
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BU of 6vzd by Molmil
N-terminal domain of mouse surfactant protein B (K46E/R51E mutant) with bound lipid
分子名称: (7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl (9Z)-octadec-9-enoate, Pulmonary surfactant-associated protein B
著者Rapoport, T.A, Bodnar, N.O.
登録日2020-02-28
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
2GTG
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BU of 2gtg by Molmil
Crystal Structure of Human Saposin C
分子名称: Proactivator polypeptide
著者Prive, G.G, Ahn, V.E.
登録日2006-04-28
公開日2006-07-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2DOB
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BU of 2dob by Molmil
Crystal Structure of Human Saposin A
分子名称: CALCIUM ION, Proactivator polypeptide
著者Prive, G.G, Ahn, V.E.
登録日2006-04-28
公開日2006-07-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of saposins A and C.
Protein Sci., 15, 2006
6VYN
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N-terminal domain of mouse surfactant protein B with bound lipid, wild type
分子名称: (7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl (9Z)-octadec-9-enoate, Pulmonary surfactant-associated protein B
著者Rapoport, T.A, Bodnar, N.O.
登録日2020-02-27
公開日2020-11-25
最終更新日2021-01-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021

 

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