1M6K
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![BU of 1m6k by Molmil](/molmil-images/mine/1m6k) | Structure of the OXA-1 class D beta-lactamase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, beta-lactamase OXA-1 | 著者 | Sun, T, Nukaga, M, Mayama, K, Braswell, E.H, Knox, J.R. | 登録日 | 2002-07-16 | 公開日 | 2003-01-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Comparison of beta-lactamases of classes A and D: 1.5A crystallographic structure of the class D OXA-1 oxacillinase PROTEIN SCI., 12, 2003
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2RL3
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![BU of 2rl3 by Molmil](/molmil-images/mine/2rl3) | Crystal structure of the OXA-10 W154H mutant at pH 7 | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase PSE-2, GLYCEROL, ... | 著者 | Vercheval, L, Kerff, F, Herman, R, Sauvage, E, Guiet, R, Charlier, P, Frere, J.-M, Galleni, M. | 登録日 | 2007-10-18 | 公開日 | 2008-10-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2V2F
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![BU of 2v2f by Molmil](/molmil-images/mine/2v2f) | Crystal structure of PBP1a from drug-resistant strain 5204 from Streptococcus pneumoniae | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BARIUM ION, PENICILLIN BINDING PROTEIN 1A | 著者 | Job, V, Carapito, R, Vernet, T, Dideberg, O, Dessen, A, Zapun, A. | 登録日 | 2007-06-05 | 公開日 | 2007-12-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Common Alterations in Pbp1A from Resistant Streptococcus Pneumoniae Decrease its Reactivity Toward {Beta}-Lactams: Structural Insights. J.Biol.Chem., 283, 2008
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1NRF
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![BU of 1nrf by Molmil](/molmil-images/mine/1nrf) | C-terminal domain of the Bacillus licheniformis BlaR penicillin-receptor | 分子名称: | REGULATORY PROTEIN BLAR1 | 著者 | Kerff, F, Charlier, P, Columbo, M.L, Sauvage, E, Brans, A, Frere, J.M, Joris, B, Fonze, E. | 登録日 | 2003-01-24 | 公開日 | 2004-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the sensor domain of the BlaR penicillin receptor from Bacillus licheniformis. Biochemistry, 42, 2003
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2UWX
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![BU of 2uwx by Molmil](/molmil-images/mine/2uwx) | Active site restructuring regulates ligand recognition in class A penicillin-binding proteins | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ... | 著者 | Macheboeuf, P, DiGuilmi, A.M, Job, V, Vernet, T, Dideberg, O, Dessen, A. | 登録日 | 2007-03-23 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins Proc.Natl.Acad.Sci.USA, 102, 2005
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6P54
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6PK0
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![BU of 6pk0 by Molmil](/molmil-images/mine/6pk0) | Crystal Structure of OXA-48 with Hydrolyzed Imipenem | 分子名称: | (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2019-06-28 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D beta-Lactamase. Acs Infect Dis., 6, 2020
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6P55
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6P99
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![BU of 6p99 by Molmil](/molmil-images/mine/6p99) | OXA-48 carbapanemase, ertapenem complex | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, CADMIUM ION, ... | 著者 | Smith, C.A, Vakulenko, S.B. | 登録日 | 2019-06-10 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase. Antimicrob.Agents Chemother., 63, 2019
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6PQI
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6P98
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![BU of 6p98 by Molmil](/molmil-images/mine/6p98) | OXA-48 carbapanemase, meropenem complex | 分子名称: | Beta-lactamase, CADMIUM ION, CALCIUM ION, ... | 著者 | Smith, C.A, Vakulenko, S.B. | 登録日 | 2019-06-10 | 公開日 | 2019-08-07 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase. Antimicrob.Agents Chemother., 63, 2019
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1H8Z
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![BU of 1h8z by Molmil](/molmil-images/mine/1h8z) | Crystal structure of the class D beta-lactamase OXA-13 | 分子名称: | BETA-LACTAMASE, SULFATE ION | 著者 | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | 登録日 | 2001-02-17 | 公開日 | 2001-07-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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1H5X
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1H8Y
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![BU of 1h8y by Molmil](/molmil-images/mine/1h8y) | Crystal structure of the class D beta-lactamase OXA-13 in complex with meropenem | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, BETA-LACTAMASE, SULFATE ION | 著者 | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | 登録日 | 2001-02-17 | 公開日 | 2001-07-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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3HBR
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![BU of 3hbr by Molmil](/molmil-images/mine/3hbr) | Crystal structure of OXA-48 beta-lactamase | 分子名称: | 1,2-ETHANEDIOL, OXA-48 | 著者 | Calderone, V, Mangani, S, Benvenuti, M, Rossolini, G.M, Docquier, J.D. | 登録日 | 2009-05-05 | 公開日 | 2009-06-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases. Chem.Biol., 16, 2009
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3FYZ
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![BU of 3fyz by Molmil](/molmil-images/mine/3fyz) | OXA-24 beta-lactamase complex with SA4-17 inhibitor | 分子名称: | (2S,3R)-2-[(7-aminocarbonyl-2-methanoyl-indolizin-3-yl)amino]-4-aminocarbonyloxy-3-methyl-3-sulfino-butanoic acid, Beta-lactamase OXA-24, TETRAETHYLENE GLYCOL | 著者 | Romero, A, Santillana, E. | 登録日 | 2009-01-23 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase. J.Am.Chem.Soc., 132, 2010
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3FZC
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![BU of 3fzc by Molmil](/molmil-images/mine/3fzc) | OXA-24 beta-lactamase complex with SA3-53 inhibitor | 分子名称: | (2S,3R)-4-(2-aminoethylcarbamoyloxy)-2-[(2-methanoylindolizin-3-yl)amino]-3-methyl-3-sulfino-butanoic acid, Beta-lactamase OXA-24, TETRAETHYLENE GLYCOL | 著者 | Romero, A, Santillana, E. | 登録日 | 2009-01-24 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase. J.Am.Chem.Soc., 132, 2010
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4MNR
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![BU of 4mnr by Molmil](/molmil-images/mine/4mnr) | Crystal Structure of D,D-Transpeptidase Domain of Peptidoglycan Glycosyltransferase from Eggerthella lenta | 分子名称: | ACETIC ACID, MAGNESIUM ION, Peptidoglycan glycosyltransferase | 著者 | Kim, Y, Wu, R, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2013-09-11 | 公開日 | 2013-09-25 | 実験手法 | X-RAY DIFFRACTION (1.653 Å) | 主引用文献 | Crystal Structure of D,D-Transpeptidase Domain of Peptidoglycan Glycosyltransferase from Eggerthella lenta To be Published
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3FV7
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![BU of 3fv7 by Molmil](/molmil-images/mine/3fv7) | OXA-24 beta-lactamase complex with SA4-44 inhibitor | 分子名称: | (2S)-2-[[2-methanoyl-7-(methoxycarbonylamino)indolizin-3-yl]amino]-3-methyl-3-sulfino-butanoic acid, Beta-lactamase OXA-24 | 著者 | Bou, G, Santillana, E, Sheri, A, Beceiro, A, Sampson, J.M, Kalp, M, Bethel, C.R, Distler, A.M, Drawz, S.M, Pagadala, S.R, Van den Akker, F, Bonomo, R.A, Romero, A, Buynak, J.D. | 登録日 | 2009-01-15 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase. J.Am.Chem.Soc., 132, 2010
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3G4P
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![BU of 3g4p by Molmil](/molmil-images/mine/3g4p) | OXA-24 beta-lactamase at pH 7.5 | 分子名称: | Beta-lactamase OXA-24 | 著者 | Santillana, E, Romero, A. | 登録日 | 2009-02-04 | 公開日 | 2010-02-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase J.Am.Chem.Soc., 132, 2010
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4N1X
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![BU of 4n1x by Molmil](/molmil-images/mine/4n1x) | Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with penicillin G | 分子名称: | OPEN FORM - PENICILLIN G, Peptidoglycan glycosyltransferase | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2013-10-04 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with penicillin G To be Published
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3IF6
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![BU of 3if6 by Molmil](/molmil-images/mine/3if6) | Crystal structure of OXA-46 beta-lactamase from P. aeruginosa | 分子名称: | 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, L(+)-TARTARIC ACID, ... | 著者 | Docquier, J.D, Benvenuti, M, Calderone, V, Giuliani, F, Kapetis, D, De Luca, F, Rossolini, G.M, Mangani, S. | 登録日 | 2009-07-24 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates Antimicrob.Agents Chemother., 54, 2010
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3ISG
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![BU of 3isg by Molmil](/molmil-images/mine/3isg) | Structure of the class D beta-lactamase OXA-1 in complex with doripenem | 分子名称: | (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase OXA-1 | 著者 | Powers, R.A. | 登録日 | 2009-08-25 | 公開日 | 2009-12-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The 1.4 A crystal structure of the class D beta-lactamase OXA-1 complexed with doripenem. Biochemistry, 48, 2009
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1FOF
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![BU of 1fof by Molmil](/molmil-images/mine/1fof) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 | 分子名称: | BETA LACTAMASE OXA-10, COBALT (II) ION, SULFATE ION | 著者 | Paetzel, M, Danel, F, de Castro, L, Mosimann, S.C, Page, M.G.P, Strynadka, N.C.J. | 登録日 | 2000-08-28 | 公開日 | 2000-10-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the class D beta-lactamase OXA-10. Nat.Struct.Biol., 7, 2000
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4QJG
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![BU of 4qjg by Molmil](/molmil-images/mine/4qjg) | Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with penicillin V | 分子名称: | (2R,4S)-5,5-dimethyl-2-{(1R)-2-oxo-1-[(phenoxyacetyl)amino]ethyl}-1,3-thiazolidine-4-carboxylic acid, Peptidoglycan glycosyltransferase | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-06-03 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with penicillin V To be Published
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