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PDB: 62 件

6MRP
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Structure of the Bovine p85a BH domain R228E mutant
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-10-15
公開日2019-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Insight into the PTEN - p85 alpha interaction and lipid binding properties of the p85 alpha BH domain.
Oncotarget, 9, 2018
2XS6
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BU of 2xs6 by Molmil
CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2
分子名称: CHLORIDE ION, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA
著者Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P.
登録日2010-09-24
公開日2010-11-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The Structure and Catalytic Mechanism of Human Sphingomyelin Phosphodiesterase Like 3A - an Acid Sphingomyelinase Homolog with a Novel Nucleotide Hydrolase Activity.
FEBS J., 283, 2016
1PBW
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STRUCTURE OF BCR-HOMOLOGY (BH) DOMAIN
分子名称: PHOSPHATIDYLINOSITOL 3-KINASE
著者Musacchio, A, Cantley, L.C, Harrison, S.C.
登録日1996-10-17
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
Proc.Natl.Acad.Sci.USA, 93, 1996
3EAP
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BU of 3eap by Molmil
Crystal structure of the RhoGAP domain of ARHGAP11A
分子名称: Rho GTPase-activating protein 11A, UNKNOWN ATOM OR ION
著者Shen, Y, Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2008-08-26
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the RhoGAP domain of ARHGAP11A
To be Published
1RGP
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GTPASE-ACTIVATION DOMAIN FROM RHOGAP
分子名称: RHOGAP
著者Barrett, T, Xiao, B, Dodson, E.J, Dodson, G, Ludbrook, S.B, Nurmahomed, K, Gamblin, S.J, Musacchio, A, Smerdon, S.J, Eccleston, J.F.
登録日1996-12-05
公開日1997-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of the GTPase-activating domain from p50rhoGAP.
Nature, 385, 1997
2EE4
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Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant
分子名称: Rho GTPase activating protein 5 variant
著者Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-15
公開日2007-08-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant
To be Published
3IUG
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Crystal structure of the RhoGAP domain of RICS
分子名称: Rho/Cdc42/Rac GTPase-activating protein RICS, UNKNOWN ATOM OR ION
著者Nedyalkova, L, Tempel, W, Tong, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2009-08-31
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of the RhoGAP domain of RICS
to be published
2EE5
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Solution structure of the N-teruminus extended RhoGAP domain from human Rho GTPase activating protein 5 variant
分子名称: Rho GTPase activating protein 5 variant
著者Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-15
公開日2007-08-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the N-teruminus extended RhoGAP domain from human Rho GTPase activating protein 5 variant
To be Published
3BYI
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Crystal structure of human Rho GTPase activating protein 15 (ARHGAP15)
分子名称: Rho GTPase activating protein 15
著者Shrestha, L, Tickle, J, Elkins, J, Burgess-Brown, N, Johansson, C, Papagrigoriou, E, Kavanagh, K, Pike, A.C.W, Ugochukwu, E, Uppenberg, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Doyle, D, Structural Genomics Consortium (SGC)
登録日2008-01-16
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Human Rho GTPase Activating Protein 15 (ARHGAP15).
To be Published
3KUQ
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Crystal structure of the DLC1 RhoGAP domain
分子名称: Rho GTPase-activating protein 7, UNKNOWN ATOM OR ION
著者Nedyalkova, L, Tempel, W, Tong, Y, MacKenzie, F, Shen, L, Zhong, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2009-11-27
公開日2010-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the DLC1 RhoGAP domain
to be published
1F7C
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CRYSTAL STRUCTURE OF THE BH DOMAIN FROM GRAF, THE GTPASE REGULATOR ASSOCIATED WITH FOCAL ADHESION KINASE
分子名称: RHOGAP PROTEIN
著者Longenecker, K.L, Derewenda, U, Sheffield, P.J, Zheng, Y, Derewenda, Z.S.
登録日2000-06-26
公開日2000-12-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the BH domain from graf and its implications for Rho GTPase recognition.
J.Biol.Chem., 275, 2000
3FK2
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Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1
分子名称: Glucocorticoid receptor DNA-binding factor 1, UNKNOWN ATOM OR ION
著者Nedyalkova, L, Tong, Y, Tempel, W, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-12-15
公開日2008-12-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1
To be Published
5C5S
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BU of 5c5s by Molmil
Crystal Structure of human Myosin 9b RhoGAP domain at 2.2 angstrom
分子名称: Unconventional myosin-IXb
著者Yi, F.S, Ren, J.Q, Feng, W.
登録日2015-06-22
公開日2015-11-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression
J.Clin.Invest., 125, 2015
3WPS
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BU of 3wps by Molmil
crystal structure of the GAP domain of MgcRacGAP(S387D)
分子名称: Rac GTPase-activating protein 1, SULFATE ION
著者Murayama, K, Kato-murayama, M, Shirouzu, M, Kitamura, T, Yokoyama, S.
登録日2014-01-15
公開日2015-01-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献crystal structure of the GAP domain of MgcRacGAP
To be Published
3W6R
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BU of 3w6r by Molmil
Crystal structure of the GAP domain of human MgcRacGAP
分子名称: Rac GTPase-activating protein 1
著者Matsuura, A, Lee, H.H.
登録日2013-02-21
公開日2014-02-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of GTPase-activating domain from human MgcRacGAP.
Biochem.Biophys.Res.Commun., 435, 2013
3WPQ
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crystal structure of the GAP domain of MgcRacGAP(S387A)
分子名称: Rac GTPase-activating protein 1
著者Murayama, K, Kato-Murayama, M, Shirouzu, M, Kitamura, T, Yokoyama, S.
登録日2014-01-15
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献crystal structure of the GAP domain of MgcRacGAP
To be Published
5JD0
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BU of 5jd0 by Molmil
crystal structure of ARAP3 RhoGAP domain
分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
著者Bao, H, Li, F, Wu, J, Shi, Y.
登録日2016-04-15
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
J.Biol.Chem., 291, 2016
5MY3
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Crystal structure of the RhoGAP domain of Rgd1p at 2.19 Angstroms resolution
分子名称: RHO GTPase-activating protein RGD1
著者Martinez, D.M, d'Estaintot, B.L, Granier, T, Hugues, M, Odaert, B, Gallois, B, Doignon, F.
登録日2017-01-25
公開日2018-01-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural evidence of a phosphoinositide-binding site in the Rgd1-RhoGAP domain.
Biochem. J., 474, 2017
2OSA
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BU of 2osa by Molmil
The Rho-GAP domain of human N-chimaerin
分子名称: N-chimaerin
著者Walker, J.R, Hong, B.S, Shen, L, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.M, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC)
登録日2007-02-05
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Rho-GAP domain from human N-chimaerin
To be Published
2OVJ
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BU of 2ovj by Molmil
The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Rac GTPase-activating protein 1
著者Shrestha, L, Papagrigoriou, E, Soundararajan, M, Elkins, J, Johansson, C, von Delft, F, Pike, A.C.W, Burgess, N, Turnbull, A, Debreczeni, J, Gorrec, F, Umeano, C, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-02-14
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
To be Published
6D85
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Structure of the Bovine p85a BH domain E217K mutant
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D81
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Structure of the Bovine p85a BH domain
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.248 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D82
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Structure of the Bovine p85a BH domain
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D87
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Structure of the Bovine p85alpha BH domain, R262T mutant
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D86
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Structure of the Bovine p85a BH domain
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018

 

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