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PDB: 21 件
3FUC
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Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue inhibitor 9-(5',5'-difluoro-5'-phosphonopentyl)-9-deazaguanine structure in a new space group with one full trimer in the asymmetric unit
分子名称: AZIDE ION, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Bochtler, M, Breer, K, Bzowska, A, Chojnowski, G, Hashimoto, M, Hikishima, S, Narczyk, M, Wielgus-Kutrowska, B, Yokomatsu, T.
登録日2009-01-14
公開日2009-12-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state.
Biochem.Biophys.Res.Commun., 391, 2010
1B8O
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PURINE NUCLEOSIDE PHOSPHORYLASE
分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, MAGNESIUM ION, PHOSPHATE ION, ...
著者Fedorov, A.A, Kicska, G.A, Fedorov, E.V, Shi, W, Tyler, P.C, Furneaux, R.H, Schramm, V.L, Almo, S.C.
登録日1999-02-02
公開日1999-02-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
Biochemistry, 40, 2001
3PNP
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF BOVINE SPLEEN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX FORMS WITH PHOSPHATE AND 9-DEAZAINOSINE
分子名称: MAGNESIUM ION, PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Pugmire, M.J, Mao, C, Ealick, S.E.
登録日1998-03-27
公開日1999-03-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The High Resolution Crystal Structure of Bovine Spleen Purine Nucleoside Phosphorylase in Complex Forms with Phosphate and 9-Deazainosine
To be Published
2AI2
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Purine nucleoside phosphorylase from calf spleen
分子名称: ((2S,3AS,4R,6S)-4-(HYDROXYMETHYL)-6-(4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-TETRAHYDROFURO[3,4-D][1,3]DIOXO L-2-YL)METHYLPHOSPHONIC ACID, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Toms, A.V, Wang, W, Li, Y, Ganem, B, Ealick, S.E.
登録日2005-07-28
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.
Acta Crystallogr.,Sect.D, 61, 2005
2AI3
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Purine nucleoside phosphorylase from calf spleen
分子名称: (2S,4R,6R,6AS)-4-(2-AMINO-6-OXO-1,6-DIHYDROPURIN-9-YL)-6-(HYDROXYMETHYL)-TETRAHYDROFURO[3,4-D][1,3]DIOXOL-2-YLPHOSPHONI C ACID, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Toms, A.V, Wang, W, Li, Y, Ganem, B, Ealick, S.E.
登録日2005-07-28
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.
Acta Crystallogr.,Sect.D, 61, 2005
4PNP
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF BOVINE SPLEEN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX FORMS WITH PHOSPHATE AND 9-DEAZAINOSINE
分子名称: PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Pugmire, M.J, Mao, C, Ealick, S.E.
登録日1998-03-30
公開日1999-03-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The High Resolution Crystal Structure of Bovine Spleen Purine Nucleoside Phosphorylase in Complex Forms with Phosphate and 9-Deazainosine
To be Published
2AI1
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Purine nucleoside phosphorylase from calf spleen
分子名称: ((2R,4R,6R,6AS)-4-(2-AMINO-6-OXO-1,6-DIHYDROPURIN-9-YL)-6-(HYDROXYMETHYL)-TETRAHYDROFURO[3,4-D][1,3]DIOXOL-2-YL)METHYLPHOSPHONIC ACID, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Toms, A.V, Wang, W, Li, Y, Ganem, B, Ealick, S.E.
登録日2005-07-28
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.
Acta Crystallogr.,Sect.D, 61, 2005
1B8N
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PURINE NUCLEOSIDE PHOSPHORYLASE
分子名称: 1,4-DIDEOXY-1,4-IMINO-1-(S)-(9-DEAZAGUANIN-9-YL)-D-RIBITOL, MAGNESIUM ION, PHOSPHATE ION, ...
著者Fedorov, A.A, Kicska, G.A, Fedorov, E.V, Strokopytov, B.V, Tyler, P.C, Furneaux, R.H, Schramm, V.L, Almo, S.C.
登録日1999-02-02
公開日1999-02-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase
Biochemistry, 41, 2002
1A9T
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-DEAZAINOSINE AND PHOSPHATE
分子名称: 1-O-phosphono-alpha-D-ribofuranose, HYPOXANTHINE, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1A9O
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH PHOSPHATE
分子名称: PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1A9S
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE AND SULFATE
分子名称: INOSINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1A9Q
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE
分子名称: HYPOXANTHINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1A9R
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH HYPOXANTHINE AND SULFATE
分子名称: HYPOXANTHINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1PBN
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PURINE NUCLEOSIDE PHOSPHORYLASE
分子名称: PURINE NUCLEOSIDE PHOSPHORYLASE
著者Mao, C, Ealick, S.E.
登録日1995-07-10
公開日1995-11-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1LVU
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Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit
分子名称: 2,6-DIAMINO-(S)-9-[2-(PHOSPHONOMETHOXY)PROPYL]PURINE, CALCIUM ION, Purine nucleoside phosphorylase
著者Bzowska, A, Koellner, G, Wielgus-Kutrowska, B, Stroh, A, Raszewski, G, Holy, A, Steiner, T, Frank, J.
登録日2002-05-29
公開日2003-09-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis
J.Mol.Biol., 342, 2004
2QPL
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Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue
分子名称: 4-amino-7-methylpyrazolo[1,5-a][1,3,5]triazin-2(1H)-one, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Pereira, H.M, Berdini, V, Cleasby, A, Garratt, R.C.
登録日2007-07-24
公開日2007-12-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue.
Febs Lett., 581, 2007
1VFN
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PURINE NUCLEOSIDE PHOSPHORYLASE
分子名称: HYPOXANTHINE, MAGNESIUM ION, PURINE-NUCLEOSIDE PHOSPHORYLASE, ...
著者Koellner, G, Bzowska, A.
登録日1996-10-08
公開日1997-11-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 A resolution.
J.Mol.Biol., 265, 1997
1FXU
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PURINE NUCLEOSIDE PHOSPHORYLASE FROM CALF SPLEEN IN COMPLEX WITH N(7)-ACYCLOGUANOSINE INHIBITOR AND A PHOSPHATE ION
分子名称: 2-AMINO-7-[2-(2-HYDROXY-1-HYDROXYMETHYL-ETHYLAMINO)-ETHYL]-1,7-DIHYDRO-PURIN-6-ONE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Luic, M, Bzowska, A, Shugar, D, Saenger, W, Koellner, G.
登録日2000-09-27
公開日2000-10-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion.
Acta Crystallogr.,Sect.D, 57, 2001
1V48
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Calf spleen purine nucleoside phosphorylase (PNP) binary complex with 9-(5,5-difluoro-5-phosphonopenthyl)guanine
分子名称: 9-(5,5-DIFLUORO-5-PHOSPHONOPENTYL)GUANINE, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Luic, M, Koellner, G, Yokomatsu, T, Shibuya, S, Bzowska, A.
登録日2003-11-11
公開日2004-08-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
Acta Crystallogr.,Sect.D, 60, 2004
1LV8
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Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit
分子名称: 2,6-DIAMINO-(S)-9-[2-(PHOSPHONOMETHOXY)PROPYL]PURINE, CALCIUM ION, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Bzowska, A, Koellner, G, Wielgus-Kutrowska, B, Stroh, A, Raszewski, G, Holy, A, Steiner, T, Frank, J.
登録日2002-05-27
公開日2003-09-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis
J.Mol.Biol., 342, 2004
1A9P
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BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-DEAZAINOSINE AND PHOSPHATE
分子名称: 9-DEAZAINOSINE, PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E.
登録日1998-04-10
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998

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