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PDB: 846 件
1T8G
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Crystal structure of phage T4 lysozyme mutant L32A/L33A/T34A/C54T/C97A/E108V
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
著者He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W.
登録日2004-05-12
公開日2004-10-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
Protein Sci., 13, 2004
1L98
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PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者Pjura, P, Mcintosh, L.P, Wozniak, J.A, Matthews, B.W.
登録日1992-07-13
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
3DN6
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1,3,5-trifluoro-2,4,6-trichlorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称: 1,3,5-trichloro-2,4,6-trifluorobenzene, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ...
著者Liu, L, Matthews, B.W.
登録日2008-07-01
公開日2008-11-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding.
J.Mol.Biol., 385, 2009
1G0P
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CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149G
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
著者Xu, J, Baase, W.A, Quillin, M.L, Matthews, B.W.
登録日2000-10-06
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
1LYE
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DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Bell, J.A, Becktel, W.J, Sauer, U, Baase, W.A, Matthews, B.W.
登録日1992-08-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissection of helix capping in T4 lysozyme by structural and thermodynamic analysis of six amino acid substitutions at Thr 59.
Biochemistry, 31, 1992
229L
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GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, GUANIDINE, ...
著者Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
登録日1997-06-26
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
260L
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AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME
分子名称: CHLORIDE ION, NICKEL (II) ION, PROTEIN (LYSOZYME)
著者Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W.
登録日1999-03-01
公開日2000-09-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site.
Protein Eng., 13, 2000
1L42
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CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称: T4 LYSOZYME
著者Daopin, S, Matthews, B.W.
登録日1991-01-28
公開日1991-10-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability.
J.Mol.Biol., 221, 1991
1QT5
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D20E MUTANT STRUCTURE OF T4 LYSOZYME
分子名称: 2-HYDROXYETHYL DISULFIDE, PROTEIN (T4 LYSOZYME)
著者Kuroki, R, Weaver, L.H, Matthews, B.W.
登録日1999-06-30
公開日1999-07-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site.
Proc.Natl.Acad.Sci.USA, 96, 1999
1LYG
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DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Bell, J.A, Becktel, W.J, Sauer, U, Baase, W.A, Matthews, B.W.
登録日1992-08-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissection of helix capping in T4 lysozyme by structural and thermodynamic analysis of six amino acid substitutions at Thr 59.
Biochemistry, 31, 1992
239L
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THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
分子名称: CHLORIDE ION, T4 LYSOZYME
著者Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
登録日1997-10-23
公開日1998-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
256L
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BACTERIOPHAGE T4 LYSOZYME
分子名称: LYSOZYME
著者Faber, H.R, Matthews, B.W.
登録日1998-02-24
公開日1998-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A mutant T4 lysozyme displays five different crystal conformations.
Nature, 348, 1990
250L
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THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
著者Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
登録日1997-10-22
公開日1998-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
1LYJ
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DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Bell, J.A, Becktel, W.J, Sauer, U, Baase, W.A, Matthews, B.W.
登録日1992-08-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissection of helix capping in T4 lysozyme by structural and thermodynamic analysis of six amino acid substitutions at Thr 59.
Biochemistry, 31, 1992
1LYF
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DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Bell, J.A, Becktel, W.J, Sauer, U, Baase, W.A, Matthews, B.W.
登録日1992-08-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissection of helix capping in T4 lysozyme by structural and thermodynamic analysis of six amino acid substitutions at Thr 59.
Biochemistry, 31, 1992
2F32
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Xray crystal structure of lysozyme mutant L20/R63A liganded to ethylguanidinium
分子名称: BETA-MERCAPTOETHANOL, Lysozyme, N-ETHYLGUANIDINE
著者Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W.
登録日2005-11-18
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein Sci., 15, 2006
5NX0
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Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at room temperature
分子名称: Endolysin
著者Gohlke, U, Loll, B, Consentius, P, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T.
登録日2017-05-09
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Phys Chem Chem Phys, 19, 2017
3HTB
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2-propylphenol in complex with T4 lysozyme L99A/M102Q
分子名称: 2-propylphenol, BETA-MERCAPTOETHANOL, Lysozyme, ...
著者Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K.
登録日2009-06-11
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site.
J.Mol.Biol., 394, 2009
2OTY
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1,2-dichlorobenzene in complex with T4 Lysozyme L99A
分子名称: 1,2-DICHLOROBENZENE, BETA-MERCAPTOETHANOL, Lysozyme, ...
著者Graves, A.P, Shoichet, B.K.
登録日2007-02-09
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Predicting absolute ligand binding free energies to a simple model site.
J.Mol.Biol., 371, 2007
2RB0
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2,6-difluorobenzylbromide complex with T4 lysozyme L99A
分子名称: 2-(bromomethyl)-1,3-difluorobenzene, Lysozyme, PHOSPHATE ION
著者Graves, A.P, Boyce, S.E, Shoichet, B.K.
登録日2007-09-17
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Rescoring docking hit lists for model cavity sites: predictions and experimental testing.
J.Mol.Biol., 377, 2008
7MWY
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Structure of the drosophila STING cyclic dinucleotide binding domain
分子名称: STING
著者Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
登録日2021-05-17
公開日2021-07-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
3C83
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Bacteriophage T4 lysozyme mutant D89A in wildtype background at room temperature
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
著者Mooers, B.H.M.
登録日2008-02-08
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein Sci., 18, 2009
109L
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STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Blaber, M, Matthews, B.W.
登録日1992-12-17
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of amino acid alpha helix propensity.
Science, 260, 1993
146L
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ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Baldwin, E, Matthews, B.W.
登録日1993-10-15
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme.
Science, 262, 1993
125L
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THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Blaber, M, Matthews, B.W.
登録日1993-05-28
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Biochemistry, 32, 1993

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