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PDB: 846 件
1G1W
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T4 LYSOZYME MUTANT C54T/C97A/Q105M
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者Quillin, M.L, Matthews, B.W.
登録日2000-10-13
公開日2001-05-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
1L49
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STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME
分子名称: T4 LYSOZYME
著者Daopin, S, Matthews, B.W.
登録日1991-01-28
公開日1991-10-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme.
J.Mol.Biol., 221, 1991
1L43
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CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称: T4 LYSOZYME
著者Daopin, S, Matthews, B.W.
登録日1991-01-28
公開日1991-10-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability.
J.Mol.Biol., 221, 1991
1CV3
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T4 LYSOZYME MUTANT L121M
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Baase, W.A, Lindstrom, J, Lu, J, Matthews, B.W.
登録日1999-08-22
公開日1999-08-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
3L2X
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Crystal Structure of Spin Labeled T4 Lysozyme Mutant 115-119RX
分子名称: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, BETA-MERCAPTOETHANOL, ...
著者Fleissner, M.R, Cascio, D, Hubbell, W.L.
登録日2009-12-15
公開日2011-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Spin Labeled T4 Lysozyme Mutant 115-119RX
To be Published
1CVK
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T4 LYSOZYME MUTANT L118A
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Baase, W.A, Lindstrom, J, Lu, J, Matthews, B.W.
登録日1999-08-23
公開日1999-11-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
242L
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THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
著者Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
登録日1997-10-23
公開日1998-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
2HUL
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Crystal structure of T4 Lysozyme S44C synthetic dimer
分子名称: GLYCEROL, Lysozyme, SULFATE ION
著者Banatao, D.R, Cascio, D, Yeates, T.O.
登録日2006-07-26
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An approach to crystallizing proteins by synthetic symmetrization.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1L61
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ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者Nicholson, H, Matthews, B.W.
登録日1991-05-06
公開日1991-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry, 30, 1991
238L
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THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
著者Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
登録日1997-10-23
公開日1998-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
245L
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THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
著者Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
登録日1997-10-22
公開日1998-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
1DYE
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DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Zhang, X, Matthews, B.W.
登録日1993-05-13
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme.
J.Mol.Biol., 235, 1994
1L27
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REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY
分子名称: T4 LYSOZYME
著者Bell, J.A, Dao-Pin, S, Matthews, B.W.
登録日1989-05-01
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability.
Science, 239, 1988
246L
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THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
著者Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
登録日1997-10-22
公開日1998-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
1L86
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SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Eriksson, A.E, Matthews, B.W.
登録日1992-01-21
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences.
J.Mol.Biol., 229, 1993
1QSB
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THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
著者Liu, R, Baase, W.A, Matthews, B.W.
登録日1999-06-20
公開日1999-07-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The introduction of strain and its effects on the structure and stability of T4 lysozyme.
J.Mol.Biol., 295, 2000
1QT7
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E11N Mutant of T4 Lysozyme
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (T4 LYSOZYME)
著者Kuroki, R, Weaver, L.H, Matthews, B.W.
登録日1999-06-30
公開日1999-07-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site.
Proc.Natl.Acad.Sci.USA, 96, 1999
226L
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GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
登録日1997-06-25
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
1G0J
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CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152S
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
著者Xu, J, Baase, W.A, Quillin, M.L, Matthews, B.W.
登録日2000-10-06
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
258L
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AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME
分子名称: CHLORIDE ION, LYSOZYME, ZINC ION
著者Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W.
登録日1999-01-05
公開日2000-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site.
Protein Eng., 13, 2000
255L
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HYDROLASE
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者Kuroki, R, Shoichet, B, Weaver, L.H, Matthews, B.W.
登録日1997-11-10
公開日1998-01-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A relationship between protein stability and protein function.
Proc.Natl.Acad.Sci.USA, 92, 1995
1ZWN
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Crystal structure of spin labeled T4 Lysozyme (V131R1B)
分子名称: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ...
著者Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L.
登録日2005-06-03
公開日2006-10-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of spin labeled T4 Lysozyme (V131R1B)
To be Published
3DN1
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Chloropentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称: 1-chloro-2,3,4,5,6-pentafluorobenzene, 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, ...
著者Liu, L, Matthews, B.W.
登録日2008-07-01
公開日2008-11-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding.
J.Mol.Biol., 385, 2009
2OU8
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Structure of Spin-labeled T4 Lysozyme Mutant T115R1 at Room Temperature
分子名称: BETA-MERCAPTOETHANOL, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
著者Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L.
登録日2007-02-09
公開日2007-06-12
最終更新日2023-08-30
実験手法EPR (1.8 Å), X-RAY DIFFRACTION
主引用文献Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
3DN2
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Bromopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称: 1-bromo-2,3,4,5,6-pentafluorobenzene, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ...
著者Liu, L, Matthews, B.W.
登録日2008-07-01
公開日2008-11-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding.
J.Mol.Biol., 385, 2009

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