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PDB: 16 件
3NB0
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BU of 3nb0 by Molmil
Glucose-6-Phosphate activated form of Yeast Glycogen Synthase
分子名称: 6-O-phosphono-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Glycogen [starch] synthase isoform 2
著者Baskaran, S, Hurley, T.D.
登録日2010-06-02
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Structural basis for glucose-6-phosphate activation of glycogen synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
5UX7
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BU of 5ux7 by Molmil
Activated state yeast Glycogen Synthase in complex with UDP-xylose
分子名称: 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase isoform 2, URIDINE-5'-DIPHOSPHATE, ...
著者Mahalingan, K.K, Hurley, T.D.
登録日2017-02-22
公開日2018-02-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Activated state yeast Glycogen Synthase in complex with UDP-xylose
To Be Published
5UW0
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BU of 5uw0 by Molmil
Activated state yGsy2p in complex with UDP-2-fluoro-2-deoxy-glucose
分子名称: 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase isoform 2, URIDINE-5'-DIPHOSPHATE, ...
著者Mahalingan, K.K, Hurley, T.D.
登録日2017-02-20
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Activated state yGsy2p in complex with UDP-2-fluoro-2-deoxy-glucose
To Be Published
4KQM
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BU of 4kqm by Molmil
Crystal structure of yeast glycogen synthase E169Q mutant in complex with glucose and UDP
分子名称: 6-O-phosphono-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Gsy2p, ...
著者Chikwana, V.M, Hurley, T.D.
登録日2013-05-15
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase.
Proc.Natl.Acad.Sci.USA, 110, 2013
3RT1
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BU of 3rt1 by Molmil
Maltodextarn bound activated state form of yeast glycogen synthase isoform 2
分子名称: 6-O-phosphono-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, PROTEIN (Glycogen [starch] synthase isoform 2), ...
著者Baskaran, S, Hurley, T.D.
登録日2011-05-02
公開日2011-08-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen.
J.Biol.Chem., 286, 2011
6U77
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BU of 6u77 by Molmil
yGsy2p in complex with small molecule
分子名称: 2-methoxy-4-(1-{2-[(2S)-1-methylpyrrolidin-2-yl]ethyl}-4-phenyl-1H-imidazol-5-yl)phenol, 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase isoform 2
著者Tang, B, Hurley, T.D.
登録日2019-08-31
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase.
J.Med.Chem., 63, 2020
3NCH
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BU of 3nch by Molmil
Yeast Glycogen Synthase (Gsy2p) Basal State Conformation
分子名称: Glycogen [starch] synthase isoform 2, SULFATE ION
著者Baskaran, S, Hurley, T.D.
登録日2010-06-04
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Structural basis for glucose-6-phosphate activation of glycogen synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
5SUK
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BU of 5suk by Molmil
G6P bound activated state of yeast glycogen synthase 2
分子名称: 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase isoform 2
著者Baskaran, S, Mahalingan, K.K, Hurley, T.D.
登録日2016-08-03
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation.
Biochemistry, 56, 2017
4KQ2
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BU of 4kq2 by Molmil
Glucose1,2cyclic phosphate bound activated state of Yeast Glycogen Synthase
分子名称: (2R,3aR,5R,6S,7S,7aR)-5-(hydroxymethyl)tetrahydro-3aH-[1,3,2]dioxaphospholo[4,5-b]pyran-2,6,7-triol 2-oxide, 6-O-phosphono-alpha-D-glucopyranose, BARIUM ION, ...
著者Chikwana, V.M, Hurley, T.D.
登録日2013-05-14
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase.
Proc.Natl.Acad.Sci.USA, 110, 2013
5VNC
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BU of 5vnc by Molmil
Glycogen synthase in complex with UDP and glucosamine
分子名称: 2-amino-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase isoform 2, ...
著者Mahalingan, K.K, Hurley, T.D.
登録日2017-04-30
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Glycogen synthase in complex with UDP and glucosamine
To Be Published
5UW4
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BU of 5uw4 by Molmil
Activated yeast Glycogen Synthase in complex with UDP glucosamine
分子名称: 2-amino-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase isoform 2, ...
著者Mahalingan, K.K, Hurley, T.D.
登録日2017-02-20
公開日2018-02-28
最終更新日2022-03-23
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Activated state yeast Glycogen Synthase in complex with UDP glucosamine
To Be Published
3NAZ
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BU of 3naz by Molmil
Basal state form of Yeast Glycogen Synthase
分子名称: Glycogen [starch] synthase isoform 2, PEPTIDE, SULFATE ION
著者Baskaran, S, Hurley, T.D.
登録日2010-06-02
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for glucose-6-phosphate activation of glycogen synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3RSZ
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BU of 3rsz by Molmil
Maltodextran bound basal state conformation of yeast glycogen synthase isoform 2
分子名称: Glycogen [starch] synthase isoform 2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Baskaran, S, Hurley, T.D.
登録日2011-05-02
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.009 Å)
主引用文献Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen.
J.Biol.Chem., 286, 2011
5UW1
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BU of 5uw1 by Molmil
Activated state yGsy2p in complex with UDP-galactose
分子名称: 6-O-phosphono-alpha-D-glucopyranose, GALACTOSE-URIDINE-5'-DIPHOSPHATE, Glycogen [starch] synthase isoform 2
著者Mahalingan, K.K, Hurley, T.D.
登録日2017-02-20
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Activated state yGsy2p in complex with UDP-galactose
To Be Published
5SUL
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BU of 5sul by Molmil
Inhibited state structure of yGsy2p
分子名称: Glycogen [starch] synthase isoform 2, URIDINE-5'-DIPHOSPHATE, URIDINE-5'-MONOPHOSPHATE
著者Mahalingan, K.K, Hurley, T.D.
登録日2016-08-03
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation.
Biochemistry, 56, 2017
3O3C
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BU of 3o3c by Molmil
Glycogen synthase basal state UDP complex
分子名称: Glycogen [starch] synthase isoform 2, SULFATE ION, URIDINE-5'-DIPHOSPHATE
著者Baskaran, S, Hurley, T.D.
登録日2010-07-23
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.512 Å)
主引用文献Structural basis for glucose-6-phosphate activation of glycogen synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010

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件を2024-07-10に公開中

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