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PDB: 23 件
4REK
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Crystal structure and charge density studies of cholesterol oxidase from Brevibacterium sterolicum at 0.74 ultra-high resolution
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION
著者Zarychta, B, Lyubimov, A, Ahmed, M, Munshi, P, Guillot, B, Vrielink, A.
登録日2014-09-23
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.74 Å)
主引用文献Cholesterol oxidase: ultrahigh-resolution crystal structure and multipolar atom model-based analysis.
Acta Crystallogr.,Sect.D, 71, 2015
4XXG
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Structure of protonated Cholesterol Oxidase from Streptomyces SA-COO
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE
著者Golden, E, Vrielink, A.
登録日2015-01-30
公開日2015-12-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Production and characterization of recombinant perdeuterated cholesterol oxidase.
Anal.Biochem., 485, 2015
1N4W
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ATOMIC RESOLUTION STRUCTURE OF CHOLESTEROL OXIDASE @ pH 7.3 (STREPTOMYCES SP. SA-COO)
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Vrielink, A, Lario, P.I.
登録日2002-11-01
公開日2004-04-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (0.92 Å)
主引用文献Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment
Nat.Chem.Biol., 2, 2006
3GYJ
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Cholesterol oxidase from Streptomyces sp. N485L mutant (0.92A)
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Lyubimov, A.Y, Vrielink, A.
登録日2009-04-03
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (0.92 Å)
主引用文献A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase.
Acta Crystallogr.,Sect.D, 65, 2009
1N1P
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ATOMIC RESOLUTION STRUCTURE OF CHOLESTEROL OXIDASE @ pH 7.4 (STREPTOMYCES SP. SA-COO)
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Vrielink, A, Lario, P.I.
登録日2002-10-18
公開日2003-10-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Atomic Resolution Density Maps Reveal Secondary Structure Dependent Differences in Electronic Distribution
J.Am.Chem.Soc., 125, 2003
3CNJ
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Cholesterol oxidase from Streptomyces sp. F359W mutant (0.95A)
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Lyubimov, A.Y, Brammer, L, Vrielink, A.
登録日2008-03-25
公開日2008-04-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献The binding and release of oxygen and hydrogen peroxide are directed by a hydrophobic tunnel in cholesterol oxidase
Biochemistry, 47, 2008
1MXT
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Atomic resolution structure of Cholesterol oxidase (Streptomyces sp. SA-COO)
分子名称: CHOLESTEROL OXIDASE, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, ...
著者Vrielink, A, Lario, P.I.
登録日2002-10-03
公開日2003-02-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Sub-atomic resolution crystal structure of cholesterol oxidase: What atomic resolution crystallography reveals about enzyme mechanism and the role of FAD cofactor in redox activity
J.Mol.Biol., 326, 2003
1N4U
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CHOLESTEROL OXIDASE FROM STREPTOMYCES @ pH 4.5 (STREPTOMYCES SP. SA-COO)
分子名称: Cholesterol oxidase, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Vrielink, A, Lario, P.I.
登録日2002-11-01
公開日2004-04-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment
Nat.Chem.Biol., 2, 2006
2GEW
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Atomic resolution structure of cholesterol oxidase @ pH 9.0 (Streptomyces sp. SA-COO)
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, ...
著者Lyubimov, A.Y, Vrielink, A.
登録日2006-03-20
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment.
Nat.Chem.Biol., 2, 2006
3B3R
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Crystal structure of Streptomyces cholesterol oxidase H447Q/E361Q mutant bound to glycerol (0.98A)
分子名称: Cholesterol oxidase, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Lyubimov, A.Y, Heard, K, Tang, H, Sampson, N.S, Vrielink, A.
登録日2007-10-22
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase
Protein Sci., 16, 2007
1N4V
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ATOMIC RESOLUTION STRUCTURE OF CHOLESTEROL OXIDASE @pH 5.8 (STREPTOMYCES SP. SA-COO)
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Vrielink, A, Lario, P.I.
登録日2002-11-01
公開日2004-04-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment
Nat.Chem.Biol., 2, 2006
3GYI
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Cholesterol oxidase from Streptomyces sp. N485D mutant (1.0A)
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Lyubimov, A.Y, Vrielink, A.
登録日2009-04-03
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase.
Acta Crystallogr.,Sect.D, 65, 2009
4XWR
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BU of 4xwr by Molmil
X-ray structure of perdeuterated Cholesterol Oxidase from Streptomyces SA-COO
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Golden, E, Vrielink, A.
登録日2015-01-29
公開日2015-12-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Production and characterization of recombinant perdeuterated cholesterol oxidase.
Anal.Biochem., 485, 2015
4U2S
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Cholesterol oxidase in the reduced state complexed with isopropanol
分子名称: Cholesterol oxidase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION
著者Golden, E.A, Vrielink, A.
登録日2014-07-18
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization.
Acta Crystallogr.,Sect.D, 70, 2014
3B6D
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Crystal Structure of Streptomyces Cholesterol Oxidase H447Q/E361Q mutant (1.2A)
分子名称: Cholesterol oxidase, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, SULFATE ION
著者Lyubimov, A.Y, Vrielink, A.
登録日2007-10-29
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase
Protein Sci., 16, 2007
4U2T
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Cholesterol oxidase in the oxidised state complexed with isopropanol
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Golden, E.A, Vrielink, A.
登録日2014-07-18
公開日2014-12-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.223 Å)
主引用文献High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization.
Acta Crystallogr.,Sect.D, 70, 2014
4U2L
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Dithionite reduced cholesterol in complex with sulfite
分子名称: (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, Cholesterol oxidase, SULFATE ION
著者Golden, E.A, Vrielink, A.
登録日2014-07-17
公開日2014-12-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.337 Å)
主引用文献High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization.
Acta Crystallogr.,Sect.D, 70, 2014
5KWF
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Joint X-ray Neutron Structure of Cholesterol Oxidase
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE
著者Golden, E, Vrielink, A, Meilleur, F, Blakeley, M.
登録日2016-07-18
公開日2017-02-01
最終更新日2024-03-06
実験手法NEUTRON DIFFRACTION (1.499 Å), X-RAY DIFFRACTION
主引用文献An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase.
Sci Rep, 7, 2017
1B4V
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CHOLESTEROL OXIDASE FROM STREPTOMYCES
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE)
著者Vrielink, A, Yue, Q.K.
登録日1998-12-30
公開日1999-01-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Biochemistry, 38, 1999
1IJH
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CHOLESTEROL OXIDASE FROM STREPTOMYCES ASN485LEU MUTANT
分子名称: CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Vrielink, A, Lario, P.I.
登録日2001-04-26
公開日2001-12-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase.
Biochemistry, 40, 2001
1B8S
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CHOLESTEROL OXIDASE FROM STREPTOMYCES GLU361GLN MUTANT
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE)
著者Vrielink, A, Yue, Q.K.
登録日1999-02-02
公開日1999-02-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Biochemistry, 38, 1999
1CBO
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CHOLESTEROL OXIDASE FROM STREPTOMYCES HIS447ASN MUTANT
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE)
著者Vrielink, A, Yue, Q.K.
登録日1999-02-26
公開日1999-03-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Biochemistry, 38, 1999
1CC2
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CHOLESTEROL OXIDASE FROM STREPTOMYCES HIS447GLN MUTANT
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE)
著者Vrielink, A, Yue, Q.K.
登録日1999-03-03
公開日1999-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Biochemistry, 38, 1999

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