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PDB: 303 件

7PYJ
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CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-10
公開日2022-03-23
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7W5Y
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BU of 7w5y by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Feng, Y.
登録日2021-11-30
公開日2022-10-26
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7ADE
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Transcription termination complex IVa
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
著者Said, N, Hilal, T, Loll, B, Wahl, C.M.
登録日2020-09-14
公開日2020-11-25
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
8E5K
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BU of 8e5k by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 21 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Wang, C.
登録日2022-08-22
公開日2022-09-07
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
7BEG
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BU of 7beg by Molmil
Structures of class I bacterial transcription complexes
分子名称: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ...
著者Ye, F.Z, Hao, M, Zhang, X.D.
登録日2020-12-23
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
6UU6
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BU of 6uu6 by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.201 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
4JK2
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BU of 4jk2 by Molmil
X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp)
分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ...
著者Murakami, K.S.
登録日2013-03-09
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.201 Å)
主引用文献Differential regulation by ppGpp versus pppGpp in Escherichia coli.
Nucleic Acids Res., 41, 2013
4ZH2
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Crystal structure of Escherichia coli RNA polymerase in complex with CBR703
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Feng, Y, Ebright, R.H.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.204 Å)
主引用文献Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
7C17
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BU of 7c17 by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA
分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2020-05-02
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
6C9Y
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BU of 6c9y by Molmil
Cryo-EM structure of E. coli RNAP sigma70 holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S.
登録日2018-01-29
公開日2018-02-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation.
J. Biol. Chem., 293, 2018
8E6X
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BU of 8e6x by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; TEC part
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Wang, C.
登録日2022-08-23
公開日2022-09-07
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
6PB6
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BU of 6pb6 by Molmil
The E. coli class-II CAP-dependent transcription activation complex at the state 2
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W.
登録日2019-06-13
公開日2020-03-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
5VSW
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BU of 5vsw by Molmil
X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Murakami, K.S, Molodtsov, V.
登録日2017-05-12
公開日2017-06-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (4.295 Å)
主引用文献Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA.
Mol. Cell, 69, 2018
7Q0J
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BU of 7q0j by Molmil
RNA polymerase elongation complex in more-swiveled conformation
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-15
公開日2022-03-23
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7ADD
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BU of 7add by Molmil
Transcription termination intermediate complex IIIa
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
著者Said, N, Hilal, T, Loll, B, Wahl, C.M.
登録日2020-09-14
公開日2020-11-25
最終更新日2021-02-03
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
8G8Z
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BU of 8g8z by Molmil
Cryo-EM structure of 3DVA component 1 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, DNA (31-MER), DNA (39-MER), ...
著者Porta, J.C, Ohi, M.D, Walter, N.G, Frank, A.T, Deb, I, Meze, K.
登録日2023-02-20
公開日2023-06-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand.
Nat.Struct.Mol.Biol., 30, 2023
6UU4
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BU of 6uu4 by Molmil
E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.305 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
3T72
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BU of 3t72 by Molmil
PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex
分子名称: PHO BOX DNA (STRAND 1), PHO BOX DNA (STRAND 2), Phosphate regulon transcriptional regulatory protein phoB, ...
著者Blanco, A.G, Canals, A, Bernues, J, Sola, M, Coll, M.
登録日2011-07-29
公開日2011-09-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (4.33 Å)
主引用文献The structure of a transcription activation subcomplex reveals how sigma (70) is recruited to PhoB promoters.
Embo J., 30, 2011
6PB4
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BU of 6pb4 by Molmil
The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W.
登録日2019-06-13
公開日2020-03-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.35 Å)
主引用文献Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
6Z9S
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BU of 6z9s by Molmil
Transcription termination intermediate complex 4
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
著者Said, N, Hilal, T, Loll, B, Wahl, M.C.
登録日2020-06-04
公開日2020-11-04
最終更新日2021-02-03
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6ALH
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BU of 6alh by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex
分子名称: DNA (29-MER), DNA (5'-D(*GP*GP*GP*CP*TP*AP*AP*TP*GP*AP*CP*GP*GP*CP*GP*AP*AP*TP*AP*CP*CP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Kang, J.Y, Darst, S.A.
登録日2017-08-07
公開日2017-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural basis of transcription arrest by coliphage HK022 Nun in anEscherichia coliRNA polymerase elongation complex.
Elife, 6, 2017
6UU8
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BU of 6uu8 by Molmil
E. coli mutant sigma-S transcription initiation complex with a 7-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, and CTP for 30 minutes)
分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU7
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BU of 6uu7 by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA and an NTP ("Old" crystal soaked with UTP, CTP, ddGTP, and dinucleotide ApG for 30 minutes)
分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
7ADB
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BU of 7adb by Molmil
Transcription termination intermediate complex 1 delta NusG
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
著者Said, N, Hilal, T, Loll, B, Wahl, C.M.
登録日2020-09-14
公開日2020-11-04
最終更新日2021-02-03
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
8E5O
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BU of 8e5o by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 24 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Wang, C.
登録日2022-08-22
公開日2022-09-07
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023

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件を2024-07-10に公開中

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