PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

HCV NS3/4A protease domain of genotype 4a with an extended linker in complex with glecaprevir
分子名称:	(3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclop ropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17, 3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide, Non-structural protein 4A,Serine protease NS3, ...
著者	Timm, J, Schiffer, C.A.
登録日	2019-06-04
公開日	2020-06-10
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.294 Å)
主引用文献	Molecular mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir and characterization of genotype-specific structural differences To Be Published

HCV NS3/4A protease domain of genotype 4a in complex with glecaprevir
分子名称:	(3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclop ropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17, 3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide, Non-structural protein 4A,Serine protease NS3, ...
著者	Timm, J, Schiffer, C.A.
登録日	2019-06-04
公開日	2020-06-10
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Molecular mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir and characterization of genotype-specific structural differences To Be Published