PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 1 件

Bruton's tyrosine kinase in complex with 3-{[4-(1-acetylpiperidin-4-yl)phenyl]amino}-5-[(3R)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]pyrazine-2-carboxamide
分子名称:	1,2-ETHANEDIOL, 5-[(3R)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide, CHLORIDE ION, ...
著者	Gajewski, S, Clifton, M.C.
登録日	2022-09-16
公開日	2023-02-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.58 Å)
主引用文献	NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts. Blood, 141, 2023