9H11
 
 | | Crystal structure of OXA-48 apoenzyme | | 分子名称: | Beta-lactamase, CHLORIDE ION, GLYCEROL | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9H16
 | | Crystal structure of OXA-405 apoenzyme | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9H15
 | | Crystal structure of OXA-163 in complex with nacubactam | | 分子名称: | (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9HPV
 | | Crystal structure of OXA-163 in complex with nacubactam (16 hour soak) | | 分子名称: | (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (2S,5R)-N-(2-azanylethoxy)-1-methanoyl-5-(oxidanylamino)piperidine-2-carboxamide, 1,2-ETHANEDIOL, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-12-16 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9H18
 | | Crystal structure of OXA-405 in complex with nacubactam | | 分子名称: | (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (2S,5R)-N-(2-azanylethoxy)-1-methanoyl-5-(oxidanylamino)piperidine-2-carboxamide, 1,2-ETHANEDIOL, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9H17
 | | Crystal structure of OXA-405 in complex with avibactam | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (2S,5R)-1-methanoyl-5-(oxidanylamino)piperidine-2-carboxamide, 1,2-ETHANEDIOL, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9H13
 | | Crystal structure of OXA-163 apoenzyme | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9H14
 | | Crystal structure of OXA-163 in complex with avibactam | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (2S,5R)-1-methanoyl-5-(oxidanylamino)piperidine-2-carboxamide, 1,2-ETHANEDIOL, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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9H12
 | | Crystal structure of OXA-48 in complex with nacubactam | | 分子名称: | (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... | | 著者 | Hoff, J.F, Goudar, K.E, Hinchliffe, P, Spencer, J. | | 登録日 | 2024-10-09 | | 公開日 | 2025-09-03 | | 最終更新日 | 2025-09-24 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like beta-lactamases.
Rsc Med Chem, 2025
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