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PDB: 5 件
9CUE
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BU of 9cue by Molmil
Human STING H232R variant bound to ABZI
分子名称: Stimulator of interferon genes protein, benzyl (3-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-1,3-benzimidazol-1-yl}propyl)carbamate
著者Sack, J.S, Critton, D.A.
登録日2024-07-26
公開日2025-06-18
最終更新日2025-07-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Orthosteric STING inhibition elucidates molecular correction of SAVI STING.
Nat Commun, 16, 2025
9CUB
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BU of 9cub by Molmil
Human STING G230A/R293Q variant bound to diABZI-a1
分子名称: 1,1'-[(2E)-but-2-ene-1,4-diyl]bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-1,3-benzimidazole-5-carboxamide}, Stimulator of interferon genes protein
著者Critton, D.A.
登録日2024-07-26
公開日2025-06-18
最終更新日2025-07-16
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Orthosteric STING inhibition elucidates molecular correction of SAVI STING.
Nat Commun, 16, 2025
9CUD
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BU of 9cud by Molmil
Human STING G230A/R293Q variant bound to diABZI-i
分子名称: (2E)-1-[(2E)-4-{(2E)-5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino]-3-methyl-2,3-dihydro-1H-1,3-benzimidazol-1-yl}-2,3-dimethylbut-2-en-1-yl]-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino]-7-[(3-methoxyphenyl)methoxy]-3-methyl-2,3-dihydro-1H-1,3-benzimidazole-5-carboxamide, Stimulator of interferon genes protein
著者Critton, D.A.
登録日2024-07-26
公開日2025-06-18
最終更新日2025-07-16
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Orthosteric STING inhibition elucidates molecular correction of SAVI STING.
Nat Commun, 16, 2025
9CUA
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BU of 9cua by Molmil
Human STING G230A/R293Q variant bound to cGAMP
分子名称: Stimulator of interferon genes protein, cGAMP
著者Sack, J.S, Critton, D.A.
登録日2024-07-26
公開日2025-06-18
最終更新日2025-07-16
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Orthosteric STING inhibition elucidates molecular correction of SAVI STING.
Nat Commun, 16, 2025
9CUC
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BU of 9cuc by Molmil
Human STING G230A/R293Q variant bound to THIQi
分子名称: (3S,4S)-2-(4-tert-butyl-3-chlorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid, Stimulator of interferon genes protein
著者Critton, D.A.
登録日2024-07-26
公開日2025-06-18
最終更新日2025-07-16
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Orthosteric STING inhibition elucidates molecular correction of SAVI STING.
Nat Commun, 16, 2025

239492

件を2025-07-30に公開中

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