9DO1
 
 | | SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun13307 | | 分子名称: | 2-methyl-N-{(1R)-1-[(2M)-2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl]ethyl}-5-{[(2R)-1-methylpyrrolidin-2-yl]methoxy}benzamide, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Ansari, A, Jadhav, P, Arnold, E, Ruiz, F.X, Wang, J. | | 登録日 | 2024-09-18 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates.
Nat Commun, 16, 2025
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9DO3
 | | SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun13317 | | 分子名称: | 1,2-ETHANEDIOL, 5-[(3S)-3,4-dimethylpiperazin-1-yl]-2-methyl-N-{(1R)-1-[(2M)-2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl]ethyl}benzamide, ACETATE ION, ... | | 著者 | Ansari, A, Jadhav, P, Arnold, E, Ruiz, F.X, Wang, J. | | 登録日 | 2024-09-18 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates.
Nat Commun, 16, 2025
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9DNU
 | | SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun13296 | | 分子名称: | 1,2-ETHANEDIOL, 2-methyl-5-[(1R,5S)-8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl]-N-{(1R)-1-[(2P)-2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl]ethyl}benzamide, ACETATE ION, ... | | 著者 | Ansari, A, Jadhav, P, Arnold, E, Ruiz, F.X, Wang, J. | | 登録日 | 2024-09-18 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates.
Nat Commun, 16, 2025
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9DOI
 | | SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun13306 | | 分子名称: | 2-methyl-N-{(1S)-1-[(2P)-2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl]ethyl}-5-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}benzamide, ACETATE ION, CHLORIDE ION, ... | | 著者 | Ansari, A, Jadhav, P, Arnold, E, Ruiz, F.X, Wang, J. | | 登録日 | 2024-09-19 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates.
Nat Commun, 16, 2025
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9DNV
 | | SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun13308 | | 分子名称: | 2-methyl-5-[(1R,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-N-{(1R)-1-[(2P)-2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl]ethyl}benzamide, ACETIC ACID, CHLORIDE ION, ... | | 著者 | Ansari, A, Jadhav, P, Arnold, E, Ruiz, F.X, Wang, J. | | 登録日 | 2024-09-18 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates.
Nat Commun, 16, 2025
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9DO5
 | | SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun12665 | | 分子名称: | 5-[2-(dimethylamino)ethoxy]-N-{(1R)-1-[(2P)-2-{1-[2-(dimethylamino)-2-oxoethyl]-1H-pyrazol-4-yl}quinolin-4-yl]ethyl}-2-methylbenzamide, ACETATE ION, CHLORIDE ION, ... | | 著者 | Ansari, A, Jadhav, P, Arnold, E, Ruiz, F.X, Wang, J. | | 登録日 | 2024-09-18 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates.
Nat Commun, 16, 2025
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