PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 3 件

Catalytic unit of PI3Kg in complex with PI3K/mTOR dual inhibitor PF-04979064
分子名称:	1-{1-[(2S)-2-hydroxypropanoyl]piperidin-4-yl}-3-methyl-8-(6-methylpyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c][1,5]naphthyridin-2-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者	Knighton, D.R, Cheng, H.
登録日	2012-11-05
公開日	2013-11-20
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. ACS Med Chem Lett, 4, 2013

Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04691502 through Structure Based Drug Design
分子名称:	2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者	Knighton, D.R.
登録日	2010-04-16
公開日	2010-06-02
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. ACS Med Chem Lett, 4, 2013

Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04691502 through Structure Based Drug Design
分子名称:	8-cyclopentyl-6-[3-(hydroxymethyl)phenyl]-4-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者	Knighton, D.R.
登録日	2010-04-16
公開日	2010-06-02
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. ACS Med Chem Lett, 4, 2013