PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 1 件

B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor
分子名称:	B-Raf proto-oncogene serine/threonine-protein kinase, N~1~-(4-chlorophenyl)-6-methyl-N~5~-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine
著者	Whittington, D.A, Epstein, L.F.
登録日	2009-07-21
公開日	2009-10-06
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Selective inhibitors of the mutant B-raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline. J.Med.Chem., 52, 2009