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PDB: 1 件

4O91
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Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1
分子名称: Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
著者Gurbani, D, Hunter, J.C, Tan, L, Westover, K.D.
登録日2013-12-31
公開日2014-07-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Discovery of Type II Inhibitors of TGF beta-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2).
J.Med.Chem., 58, 2015

223532

件を2024-08-07に公開中

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