PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with N-(N-(4-amino-3,5- dichlorobenzyl)carbamimidoyl)-3-(4-methoxyphenyl)-5- methyl-4-isothiazolecarboxamide
分子名称:	Beta-secretase 1, IODIDE ION, N-[N-(4-amino-3,5-dichlorobenzyl)carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
著者	Muckelbauer, J.K.
登録日	2012-06-27
公開日	2012-10-10
最終更新日	2019-07-17
実験手法	X-RAY DIFFRACTION (2.65 Å)
主引用文献	Acyl guanidine inhibitors of beta-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesis J.Med.Chem., 55, 2012

Crystal structure of beta-site app-cleaving enzyme 1 (BACE-DB-MUT) complex with N-(N-(4- acetamido-3-chloro-5-methylbenzyl)carbamimidoyl)-3-(4- methoxyphenyl)-5-methyl-4-isothiazolecarboxamide
分子名称:	Beta-secretase 1, IODIDE ION, N-{N-[4-(acetylamino)-3-chloro-5-methylbenzyl]carbamimidoyl}-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
著者	Muckelbauer, J.K.
登録日	2012-06-27
公開日	2012-10-10
最終更新日	2019-07-17
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Acyl Guanidine Inhibitors of beta-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis J.Med.Chem., 55, 2012