6SD9
| Crystal structure of wild-type cMET bound by foretinib | 分子名称: | CHLORIDE ION, Hepatocyte growth factor receptor, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | 著者 | Collie, G.W, Phillips, C. | 登録日 | 2019-07-26 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors. Acs Med.Chem.Lett., 10, 2019
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6SDC
| Crystal structure of D1228V cMET bound by foretinib | 分子名称: | Hepatocyte growth factor receptor, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | 著者 | Collie, G.W, Phillips, C. | 登録日 | 2019-07-26 | 公開日 | 2019-08-14 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors. Acs Med.Chem.Lett., 10, 2019
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6SDD
| Crystal structure of D1228V cMET bound by BMS-777607 | 分子名称: | GLYCEROL, Hepatocyte growth factor receptor, N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | 著者 | Collie, G.W, Phillips, C. | 登録日 | 2019-07-26 | 公開日 | 2019-08-14 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors. Acs Med.Chem.Lett., 10, 2019
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6SDE
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