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PDB: 4 件

6SD9
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BU of 6sd9 by Molmil
Crystal structure of wild-type cMET bound by foretinib
分子名称: CHLORIDE ION, Hepatocyte growth factor receptor, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
著者Collie, G.W, Phillips, C.
登録日2019-07-26
公開日2019-08-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors.
Acs Med.Chem.Lett., 10, 2019
6SDC
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BU of 6sdc by Molmil
Crystal structure of D1228V cMET bound by foretinib
分子名称: Hepatocyte growth factor receptor, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
著者Collie, G.W, Phillips, C.
登録日2019-07-26
公開日2019-08-14
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors.
Acs Med.Chem.Lett., 10, 2019
6SDD
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BU of 6sdd by Molmil
Crystal structure of D1228V cMET bound by BMS-777607
分子名称: GLYCEROL, Hepatocyte growth factor receptor, N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
著者Collie, G.W, Phillips, C.
登録日2019-07-26
公開日2019-08-14
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors.
Acs Med.Chem.Lett., 10, 2019
6SDE
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BU of 6sde by Molmil
Crystal structure of wild-type cMET bound by savolitinib
分子名称: Hepatocyte growth factor receptor, volitinib
著者Collie, G.W, Phillips, C.
登録日2019-07-26
公開日2019-08-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors.
Acs Med.Chem.Lett., 10, 2019

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件を2024-06-12に公開中

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