PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 3 件

PAK1 in complex with 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine
分子名称:	2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine, MAGNESIUM ION, Serine/threonine-protein kinase PAK 1
著者	Gutmann, S, Rummel, G.
登録日	2015-04-29
公開日	2015-06-24
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (1.99 Å)
主引用文献	Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015

PAK1 in complex with (S)-N-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide
分子名称:	(S)-N-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide, MAGNESIUM ION, Serine/threonine-protein kinase PAK 1
著者	Gutmann, S, Rummel, G.
登録日	2015-04-29
公開日	2015-06-24
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015

Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1
分子名称:	2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, GLYCEROL, Serine/threonine-protein kinase PAK 1
著者	Bellamacina, C.R, Bussiere, D.E.
登録日	2015-05-01
公開日	2015-08-05
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015