6IWI
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![BU of 6iwi by Molmil](/molmil-images/mine/6iwi) | Crystal structure of PDE5A in complex with a novel inhibitor | 分子名称: | MAGNESIUM ION, N-[3-(4,5-diethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-4-propoxyphenyl]-2-(4-methylpiperazin-1-yl)acetamide, ZINC ION, ... | 著者 | Zhang, X.L, Xu, Y.C. | 登録日 | 2018-12-05 | 公開日 | 2019-12-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.155 Å) | 主引用文献 | Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension. J.Med.Chem., 62, 2019
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