9E1K
 
 | | Discovery of Potent, Highly Selective and Efficacious SMARCA2 Degraders - Compound 11 | | 分子名称: | (12S)-4-bromo-7,7-dimethyl-9-(piperidin-4-yl)indolo[1,2-a]quinazolin-5(7H)-one, Isoform Short of Probable global transcription activator SNF2L2, ZINC ION | | 著者 | Strickland, C, Rice, C. | | 登録日 | 2024-10-21 | | 公開日 | 2024-12-18 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders.
J.Med.Chem., 68, 2025
|
|
9E31
 | | Discovery of Potent, Highly Selective and Efficacious SMARCA2 Degraders - Compound 6 | | 分子名称: | (12'R)-4'-chloro-9'-(piperidin-4-yl)-5'H-spiro[cyclohexane-1,7'-indolo[1,2-a]quinazolin]-5'-one, ACETATE ION, Isoform Short of Probable global transcription activator SNF2L2, ... | | 著者 | Strickland, C, Rice, C. | | 登録日 | 2024-10-23 | | 公開日 | 2024-12-18 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders.
J.Med.Chem., 68, 2025
|
|
9E30
 | | Discovery of Potent, Highly Selective and Efficacious SMARCA2 Degraders - Compound 13 | | 分子名称: | (12'S)-4'-chloro-10'-(piperidin-4-yl)-5'H-spiro[cyclohexane-1,7'-indolo[1,2-a]quinazolin]-5'-one, ACETATE ION, Isoform Short of Probable global transcription activator SNF2L2, ... | | 著者 | Strickland, C, Rice, C. | | 登録日 | 2024-10-23 | | 公開日 | 2024-12-18 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders.
J.Med.Chem., 68, 2025
|
|
