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PDB: 1 件

8U8X
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crystal structure of the receptor tyrosine kinase Human HER2 (ERBB2) YVMA mutant kinase domain in complex with inhibitor compound 27
分子名称: 1-{(1R,3r,5S)-3-[(3M)-4-methyl-3-{3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl}-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-8-azabicyclo[3.2.1]octan-8-yl}propan-1-one, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Wang, J, Mou, T.C.
登録日2023-09-18
公開日2024-06-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Discovery of Potent and Selective Covalent Inhibitors of HER2 WT and HER2 YVMA .
J.Med.Chem., 67, 2024

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件を2024-11-06に公開中

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