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PDB: 2 件

8XAR
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BU of 8xar by Molmil
Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with SAM and Compound 54
分子名称: 1,2-ETHANEDIOL, 7-chloranyl-2-ethyl-5-pyridin-3-yl-pyrazolo[3,4-c]quinolin-4-one, CHLORIDE ION, ...
著者Zheng, J.Y, Zhang, G.P, Li, J.J, Tong, S.L.
登録日2023-12-05
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy.
J.Med.Chem., 67, 2024
8XB0
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BU of 8xb0 by Molmil
Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with SAM and Compound 292
分子名称: 1,2-ETHANEDIOL, 7-chloranyl-5-(2-cyclopropylpyridin-3-yl)-8-fluoranyl-2-methyl-pyrazolo[3,4-c]quinolin-4-one, CHLORIDE ION, ...
著者Tong, S.L, Zhang, G.P.
登録日2023-12-05
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy.
J.Med.Chem., 67, 2024

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件を2024-07-10に公開中

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