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PDB: 1 件

7XMK
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Crystal structure of human RIPK1 kinase domain in complex with compound SKLB923
分子名称: 5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1
著者Zhang, L, Wang, Y, Li, Y, Yang, S.
登録日2022-04-26
公開日2023-04-26
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.376 Å)
主引用文献From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases.
J.Med.Chem., 67, 2024

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件を2024-07-10に公開中

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