8OU3
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 8d | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-fluoranyl-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Maiwald, S, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU5
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11b | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-(trifluoromethyl)benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU7
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11d | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methoxy-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU4
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11a | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-chloranyl-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU9
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11e | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-oxidanyl-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU6
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11c | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methyl-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OUA
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11f | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2,5-bis(fluoranyl)-3-methoxy-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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