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PDB: 2 件

7P3V
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BU of 7p3v by Molmil
B-Raf V600E structure bound to a new inhibitor
分子名称: Serine/threonine-protein kinase B-raf, ~{N}-[3-[5-(2-azanylpyrimidin-4-yl)-2-[(3~{S})-morpholin-3-yl]-1,3-thiazol-4-yl]-2-fluoranyl-phenyl]-2,5-bis(fluoranyl)benzenesulfonamide
著者Schneider, M, Gelin, M, Cohen-Gonsaud, M, Labesse, G.
登録日2021-07-08
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding.
J.Med.Chem., 65, 2022
6HJ2
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BU of 6hj2 by Molmil
Crystal structure of hPXR in complex with dabrafenib
分子名称: Dabrafenib, ISOPROPYL ALCOHOL, Nuclear receptor subfamily 1 group I member 2
著者Granell, M, Delfosse, V, Bourguet, W.
登録日2018-08-31
公開日2020-03-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding.
J.Med.Chem., 65, 2022

223790

件を2024-08-14に公開中

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