PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Compound 24
分子名称:	6-(4-amino-4-methylpiperidin-1-yl)-3-[(2,3-dichlorophenyl)sulfanyl]pyrazin-2-amine, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
著者	Fodor, M, Stams, T.
登録日	2020-08-21
公開日	2020-09-23
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.917 Å)
主引用文献	Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer. J.Med.Chem., 63, 2020

Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor TNO155
分子名称:	(3S,4S)-8-{6-amino-5-[(2-amino-3-chloropyridin-4-yl)sulfanyl]pyrazin-2-yl}-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
著者	Fodor, M, Stams, T.
登録日	2020-08-21
公開日	2020-09-23
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.166 Å)
主引用文献	Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer. J.Med.Chem., 63, 2020