9V92
 
 | | Crystal structure of the Pin1 and Frag61 complex | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J. | | 登録日 | 2025-05-30 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JYR
 | | Crystal structure of the PIN1 and fragment 4 complex | | 分子名称: | 1H-indol-4-ylmethanol, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-12 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JYO
 | | Crystal structure of the Pin1 and fragment 2 complex. | | 分子名称: | 2-(4-aminophenyl)ethanoic acid, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-12 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JZU
 | | Crystal structure of the PIN1 and fragment 14 complex. | | 分子名称: | 1-(1H-pyrrol-3-yl)ethanone, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-14 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KF0
 | | Crystal structure of the PIN1 and fragment 32 complex. | | 分子名称: | (2,5-dimethylpyrazol-3-yl)methanol, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-05 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JZ3
 | | Crystal structure of the PIN1 and fragment 8 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 3H-benzimidazol-5-ylmethanol, CHLORIDE ION, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-13 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KES
 | | Crystal structure of the PIN1 and fragment 28 complex. | | 分子名称: | (3-pyrimidin-5-ylphenyl)methanol, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-05 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JZ2
 | | Crystal structure of the PIN1 and fragment 7 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, N-(5-azanyl-2-methyl-phenyl)ethanamide, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-13 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KXH
 | | Crystal structure of the PIN1 and fragment 42 complex | | 分子名称: | 2,6-bis(fluoranyl)benzamide, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-12-06 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JZG
 | | Crystal structure of the PIN1 and fragment 12 complex. | | 分子名称: | 2-(4-hydroxyphenyl)ethanamide, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-14 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JZ4
 | | Crystal structure of the PIN1 and fragment 9 complex. | | 分子名称: | 1,3-dihydro-2-benzofuran-5-amine, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-13 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KEB
 | | Crystal structure of the PIN1 and fragment 24 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-04 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KE7
 | | Crystal structure of the PIN1 and fragment 23 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, N-ethyl-4-fluoranyl-benzenesulfonamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-04 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KXM
 | | Crystal structure of the PIN1 and fragment 57 complex. | | 分子名称: | (1~{S})-1-(1~{H}-benzimidazol-2-yl)ethanol, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-12-06 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JYP
 | | Crystal structure of the PIN1 and fragment 3 complex | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-oxidanylidene-4-thiophen-2-yl-butanoic acid, CHLORIDE ION, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-12 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JZV
 | | Crystal structure of the PIN1 and fragment 15 complex. | | 分子名称: | 1,3-dimethylimidazolidin-2-one, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-14 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KEL
 | | Crystal structure of the PIN1 and fragment 26 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 6-Quinolinylmethanol, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-05 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KEQ
 | | Crystal structure of the PIN1 and fragment 27 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 3-(4-methylpiperazin-1-yl)aniline, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-05 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KXN
 | | Crystal structure of the PIN1 and fragment 58 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 5-methyl-1,2-oxazole-3-carbohydrazide, CHLORIDE ION, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-12-06 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KFH
 | | Crystal structure of the PIN1 and fragment 52 complex | | 分子名称: | 2-methylfuran-3-carboxylic acid, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-06 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KXJ
 | | Crystal structure of the PIN1 and fragment 53 complex | | 分子名称: | (3S,11R)-tetracyclo[6.3.0.02,6.05,9]undecane-3,11-diol, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-12-06 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JZ6
 | | Crystal structure of the PIN1 and fragment 11 complex. | | 分子名称: | 1,3,4-thiadiazol-2-amine, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-14 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KE9
 | | Crystal structure of the PIN1 and fragment 22 complex. | | 分子名称: | (2H-1,3-benzodioxol-5-yl)methanol, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-04 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9JYV
 | | Crystal structure of the PIN1 and fragment 6 complex. | | 分子名称: | 1-methylpyridin-2-one, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-10-12 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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9KEC
 | | Crystal structure of the PIN1 and fragment 25 complex. | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, N-[(4-fluorophenyl)methyl]-4-oxidanyl-butanamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. | | 登録日 | 2024-11-04 | | 公開日 | 2025-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Uncovering druggable hotspots on Pin1 via X-ray crystallographic fragment screening.
Eur.J.Med.Chem., 299, 2025
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