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PDB: 1 件

9H0F
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SARS-CoV-2 Mpro in complex with a silicon-containing inhibitor
分子名称: 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Andrews-Clark, T.C, Laczi, D, Schoenbauer, S, Brewitz, L, Schofield, C.J, Walsh, M.
登録日2024-10-08
公開日2025-06-11
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Silaproline-bearing nirmatrelvir derivatives are potent inhibitors of the SARS-CoV-2 main protease highlighting the value of silicon-derivatives in structure-activity-relationship studies.
Eur J Med Chem, 291, 2025

245663

件を2025-12-03に公開中

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