9D17
 
 | | Crystal structure of the catalytic region of human MASP-2 with specific inhibitor Compound S1 | | 分子名称: | 2-(2-amino-1H-1,3-benzimidazol-1-yl)-N-(5-ethylpyridin-2-yl)acetamide, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Sawyer, T.K, Wibowo, A.S, Carter, J, Moussa, S.H. | | 登録日 | 2024-08-07 | | 公開日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3.
Eur.J.Med.Chem., 289, 2025
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9D3Y
 | | Crystal structure of the catalytic region of human MASP-2 with specific inhibitor Compound S2 | | 分子名称: | (2S)-N-[2-(2-amino-1H-1,3-benzimidazol-5-yl)ethyl]-1-[(2R,4S)-4-phenylpiperidine-2-carbonyl]azetidine-2-carboxamide, GLYCEROL, Mannan-binding lectin serine protease 2 B chain | | 著者 | Sawyer, T.K, Wibowo, A.S, Carter, J, Moussa, S.H. | | 登録日 | 2024-08-12 | | 公開日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3.
Eur.J.Med.Chem., 289, 2025
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9D4D
 | | Crystal structure of the catalytic region of human MASP-2 with specific inhibitor Compound S3 | | 分子名称: | 2-(2-amino-1H-1,3-benzimidazol-4-yl)-N-{4-[(pyridin-4-yl)methyl]phenyl}acetamide, GLYCEROL, Mannan-binding lectin serine protease 2 B chain | | 著者 | Sawyer, T.K, Wibowo, A.S, Carter, J, Moussa, S.H. | | 登録日 | 2024-08-12 | | 公開日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3.
Eur.J.Med.Chem., 289, 2025
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9D40
 | | Crystal structure of the catalytic region of human MASP-2 with specific inhibitor Analog 20 | | 分子名称: | GLYCEROL, Mannan-binding lectin serine protease 2 B chain, N-{[4-(2-amino-1H-imidazol-4-yl)phenyl]methyl}-2-[4-(benzenesulfonamido)phenyl]acetamide | | 著者 | Sawyer, T.K, Wibowo, A.S, Carter, J, Moussa, S.H. | | 登録日 | 2024-08-12 | | 公開日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3.
Eur.J.Med.Chem., 289, 2025
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