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PDB: 1 件

8WD4
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EGFR(L858R/T790/C797S) in complex with compound 5j
分子名称: CHLORIDE ION, Epidermal growth factor receptor, ~{N}-[3,3-bis(fluoranyl)propyl]-4-[[(2~{S})-butan-2-yl]amino]-6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]pyridine-3-carboxamide
著者Nishikawa, Y.
登録日2023-09-14
公開日2023-12-20
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Synthesis, activity, and their relationships of 2,4-diaminonicotinamide derivatives as EGFR inhibitors targeting C797S mutation.
Bioorg.Med.Chem.Lett., 98, 2023

222926

件を2024-07-24に公開中

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