PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 3 件

CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 4)
分子名称:	4-(benzylamino)-6-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]pyridine-3-carboxamide, Interleukin-1 receptor-associated kinase 4
著者	Sack, J.S.
登録日	2017-06-21
公開日	2017-10-11
最終更新日	2017-10-25
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017

CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 9)
分子名称:	6-[(1,3-benzothiazol-6-yl)amino]-4-{[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino}-N-methylpyridine-3-carboxamide, Interleukin-1 receptor-associated kinase 4
著者	Sack, J.S.
登録日	2017-06-21
公開日	2017-10-11
最終更新日	2017-10-25
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017

CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 7)
分子名称:	4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide, Tyrosine-protein kinase JAK3
著者	Sack, J.S.
登録日	2017-06-21
公開日	2017-10-11
最終更新日	2017-10-25
実験手法	X-RAY DIFFRACTION (2.61 Å)
主引用文献	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017