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PDB: 3 件

Potent and Selective Inhibitors of PI3K-delta: Obtaining Isoform Selectivity from the Affinity Pocket and Tryptophan Shelf
分子名称:	2-(1-{[2-(5-fluoro-1H-indol-4-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者	Murray, J.M.
登録日	2012-05-02
公開日	2013-04-17
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.67 Å)
主引用文献	Potent and selective inhibitors of PI3K-delta: obtaining isoform selectivity from the affinity pocket and tryptophan shelf Bioorg.Med.Chem.Lett., 22, 2012

Potent and Selective Inhibitors of PI3K-delta: Obtaining Isoform Selectivity from the Affinity Pocket and Tryptophan Shelf
分子名称:	2-(1-{[2-(2H-indazol-4-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者	Murray, J.M.
登録日	2012-05-02
公開日	2013-04-17
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.803 Å)
主引用文献	Potent and selective inhibitors of PI3K-delta: obtaining isoform selectivity from the affinity pocket and tryptophan shelf Bioorg.Med.Chem.Lett., 22, 2012

Potent and Selective Inhibitors of PI3K-delta: Obtaining Isoform Selectivity from the Affinity Pocket and Tryptophan Shelf
分子名称:	2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者	Murray, J.M.
登録日	2012-05-02
公開日	2013-04-17
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.94 Å)
主引用文献	Potent and selective inhibitors of PI3K-delta: obtaining isoform selectivity from the affinity pocket and tryptophan shelf Bioorg.Med.Chem.Lett., 22, 2012