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PDB: 1 件

Bace1 in complex with the aminohydantoin Compound 102
分子名称:	(5R)-2-amino-5-[4-(difluoromethoxy)phenyl]-5-[4-fluoro-3-(5-fluoropent-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1
著者	Olland, A.M.
登録日	2010-08-31
公開日	2011-08-31
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Design and Synthesis of Aminohydantoins as Potent and Selective Human beta-Secretase (BACE1) Inhibitors with Enhanced Brain Permeability Bioorg.Med.Chem.Lett., 20, 2010