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PDB: 1 件

3LOX
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BU of 3lox by Molmil
HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound
分子名称: (1R,2S,5S)-N-[(2S,3R)-4-amino-1-cyclobutyl-3-hydroxy-4-oxobutan-2-yl]-6,6-dimethyl-3-{3-methyl-N-[(1-methylcyclohexyl)c arbamoyl]-L-valyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide, BETA-MERCAPTOETHANOL, HCV NS3 Protease, ...
著者Prongay, A.J.
登録日2010-02-04
公開日2011-02-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor.
Bioorg.Med.Chem.Lett., 20, 2010

223532

件を2024-08-07に公開中

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