9J7G
 
 | | Crystal strcuture of Keap1_compound_8 | | 分子名称: | 2-[(4-aminophenyl)sulfonyl-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]amino]ethanamide, Kelch-like ECH-associated protein 1, ~{N}-[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]-3-[2-[2-[2-[3-[[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]ethoxy]propanamide | | 著者 | Xu, K. | | 登録日 | 2024-08-18 | | 公開日 | 2025-06-25 | | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | | 主引用文献 | Chemical knockdown of Keap1 and homoPROTAC-ing allergic rhinitis
Acta Pharm Sin B, 2025
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9J70
 | | Crystal structure of Keap1 dimer | | 分子名称: | Kelch-like ECH-associated protein 1 | | 著者 | Xu, K. | | 登録日 | 2024-08-17 | | 公開日 | 2025-06-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Chemical knockdown of Keap1 and homoPROTAC-ing allergic rhinitis
Acta Pharm Sin B, 2025
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9J71
 | | Crystal strcuture of Keap1_compound_7 | | 分子名称: | 2-[(4-aminophenyl)sulfonyl-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]amino]ethanamide, Kelch-like ECH-associated protein 1, ~{N}-[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]-3-[2-[2-[3-[[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]propanamide | | 著者 | Xu, K. | | 登録日 | 2024-08-17 | | 公開日 | 2025-06-25 | | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | | 主引用文献 | Chemical knockdown of Keap1 and homoPROTAC-ing allergic rhinitis
Acta Pharm Sin B, 2025
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9J7F
 | | Crystal strcuture of Keap1_compound_1 | | 分子名称: | Kelch-like ECH-associated protein 1, ~{N},~{N}'-bis[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]pentanediamide | | 著者 | Xu, K. | | 登録日 | 2024-08-18 | | 公開日 | 2025-06-25 | | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | | 主引用文献 | Chemical knockdown of Keap1 and homoPROTAC-ing allergic rhinitis
Acta Pharm Sin B, 2025
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